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NCT06744296 · ClinicalTrials.gov registry record
Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck
A clinical trial of Squamous Cell Carcinoma of Head and Neck, sponsored by Massachusetts Eye and Ear Infirmary.
- Recruiting
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT06744296: Recruiting study of Squamous Cell Carcinoma of Head and Neck, sponsored by Massachusetts Eye and Ear Infirmary.
NCT06744296 is a study of Squamous Cell Carcinoma of Head and Neck that is actively recruiting participants, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 75 participants, below the 168-participant average among 37 other Squamous Cell Carcinoma of Head and Neck trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06744296, a study of Squamous Cell Carcinoma of Head and Neck, is actively recruiting participants, sponsored by Massachusetts Eye and Ear Infirmary.
- RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test the ability of a personalized blood test to determine which head and neck cancer patients will have a recurrence after treatment.
Primary Outcome
2-year disease-free survival (DFS) in patients with detectable vs no detectable ctDNA two weeks after treatment completion
Conditions Studied
Interventions
- OTHER Blood Draws and Tissue Sample(s)
Study Locations (1)
Massachusetts
- Massachusetts Eye and Ear - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2025-02-03 |
| Est. Completion | 2029-01-06 |
What NCT06744296 shows while recruiting
NCT06744296 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 168-participant average among 37 other Squamous Cell Carcinoma of Head and Neck trials with a reported enrollment target (55% lower).
The record links to 1 condition, with Squamous Cell Carcinoma of Head and Neck appearing as the primary indexed condition, and to 1 intervention - of which Blood Draws and Tissue Sample(s) is the first listed.
NCT06744296 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06744296 about?
NCT06744296 is a clinical study titled "Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck". This study will test the ability of a personalized blood test to determine which head and neck cancer patients will have a recurrence after treatment.
What is the current status of trial NCT06744296?
This trial is currently recruiting. The enrollment target is 75 participants. The study started on 2025-02-03. Estimated completion is 2029-01-06.
What conditions does trial NCT06744296 study?
This clinical trial studies the following conditions: Squamous Cell Carcinoma of Head and Neck.
What interventions are being tested in trial NCT06744296?
The interventions under investigation include: Blood Draws and Tissue Sample(s) (OTHER).
Who is sponsoring clinical trial NCT06744296?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06744296 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Squamous Cell Carcinoma of Head and Neck
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Where NCT06744296's enrollment target sits among peer trials
75 18th of 37 higher than 20 of 37 other Squamous Cell Carcinoma of Head and Neck trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Squamous Cell Carcinoma of Head and Neck trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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