Massachusetts Eye and Ear Infirmary

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts Eye and Ear Infirmary sits in the top decile of US sponsors by registered trial count (#295 of 15,742 sponsors by registered trial count).

73 total trials 20 currently recruiting 36 completed early-phase tilt top decile by trial count

Massachusetts Eye and Ear Infirmary: 73 sponsored US clinical trials, 20 recruiting.

Massachusetts Eye and Ear Infirmary sponsors 73 registered US clinical trials on ClinicalTrials.gov, 20 of them currently recruiting, and 36 completed. 8 of these trials are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Spasmodic Dysphonia, with 4 trials.

Top-decile sponsor footprint

Massachusetts Eye and Ear Infirmary ranks in the top decile of sponsors by registered trial count (#295 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

36 of 44 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

73 total, page 2 of 2

TERMINATED NA

Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects

NCT01864291

COMPLETED Phase 4

Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial

NCT01919411

COMPLETED NA

Binocular Treatment of Amblyopia Before and After Strabismus Surgery

NCT01791946

TERMINATED NA

Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects

NCT01736267

COMPLETED Phase 2

Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy

NCT01605903

TERMINATED

In Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions

NCT01993654

COMPLETED Phase 4

Efficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis

NCT01456780

COMPLETED

Study to Evaluate the Efficacy of Optical Imaging to Evaluate the Anatomy of the Developing Pediatric Vocal Fold

NCT01810107

TERMINATED Phase 4

Effects of Anti-Glaucoma Medications on the Ocular Surface

NCT01315574

COMPLETED

Randomized Controlled Trial of Voice on Children With Vocal Nodules

NCT01255735

COMPLETED NA

The Effects of Caffeinated Coffee on Intraocular Pressure

NCT01364207

COMPLETED

Comparison of Four Different Aberrometers for Evaluation of Higher Order Visual Aberrations

NCT01230164

COMPLETED Phase 4

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

NCT01250925

COMPLETED NA

Evaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy

NCT01415583

COMPLETED NA

Effect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure Glaucoma

NCT01105065

COMPLETED NA

PEMF: an Adjunct Therapy for Anterior Uveitis

NCT01154010

COMPLETED NA

Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)

NCT00824824

COMPLETED Phase 1

Ranibizumab in Combination With Proton Beam Irradiation for Choroidal Melanoma

NCT00765921

COMPLETED

Intraoperative Laryngeal Electromyography (LEMG) in Children With Vocal Fold Immobility: a Longitudinal Study

NCT00771186

TERMINATED Phase 4

The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye

NCT00553735

COMPLETED Phase 1

Topical Avastin for Treatment of Corneal Neovascularization

NCT00559936

COMPLETED

Multi-Center, Randomized Trial of the Pulsed Dye Laser for JORRP

NCT00550914

COMPLETED Phase 3

Sudden Deafness Treatment Trial

NCT00097448

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What is open in the Massachusetts Eye and Ear Infirmary pipeline

20 recruiting of 73 indexed (27% open); 36 completed (49%).

Phase mix: 8 late (III/IV) vs 22 early (I/II) (early-phase heavy).

Top condition: Spasmodic Dysphonia (4 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Massachusetts Eye and Ear Infirmary: open-pipeline peers nationwide

Peers matched on 73 registered trials and 27% open enrollment, not the therapeutic-area sidebar.

Massachusetts Eye and Ear Infirmary sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080 0%10%20%30%40% Total trials Recruiting share Massachusetts Eye and Ear InfirmaryDenver Health and Hospital AuthorityHugo W. Moser Research Institute at Kennedy KriegerJoslin Diabetes CenterTulane UniversityConnecticut Children's Medical CenterCriteriumMinneapolis Heart Institute FoundationNerviano Medical Sciences
Massachusetts Eye and Ear Infirmary sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Massachusetts Eye and Ear Infirmary sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 73 trials (± recruiting share)

Sponsors near 27% open enrollment (± trial volume)

What to do with this Massachusetts Eye and Ear Infirmary page

73 registered trials is a research-attention snapshot, not an endorsement of Massachusetts Eye and Ear Infirmary or any single study.

  • 20 of Massachusetts Eye and Ear Infirmary's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Spasmodic Dysphonia is the condition Massachusetts Eye and Ear Infirmary studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Spasmodic Dysphonia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Massachusetts Eye and Ear Infirmary pipeline card: 73 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.