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NCT04735263 · ClinicalTrials.gov registry record · Phase 2

Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD

A Phase 2 study of Age-related Macular Degeneration, sponsored by Massachusetts Eye and Ear Infirmary.

Recruiting
Registry status
Phase 2
Development phase
21
Enrollment target
1
Study location

NCT04735263 is a Phase 2 study of Age-related Macular Degeneration that is actively recruiting participants, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 21 participants, below the 1,507-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04735263, a Phase 2 study of Age-related Macular Degeneration, is actively recruiting participants, sponsored by Massachusetts Eye and Ear Infirmary.

RECRUITING
Registry status
Phase 2
Development phase
21 participants
Enrollment target
1
Study location

Study Summary

interventional trial for off label use of high dose atorvastatin 80 mg in intermediate AMD patients and correlate recovery response measured by dark adaptation recovery time with drusen volume reduction measured by SD-OCT

Interventions

  • DRUG Atorvastatin 80mg

Study Locations (1)

Massachusetts

  • Massachusetts Eye and Ear Infirmary - Boston

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2021-02-04
Est. Completion 2028-01-01
Phase Phase 2

What the Registry Record Tells You About NCT04735263

The ClinicalTrials.gov registry entry for NCT04735263 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,507-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (99% lower). The listed sponsor is Massachusetts Eye and Ear Infirmary, which has 73 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 1 intervention - of which Atorvastatin 80mg is the first listed.

NCT04735263 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04735263 about?

NCT04735263 is a clinical study titled "Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD". interventional trial for off label use of high dose atorvastatin 80 mg in intermediate AMD patients and correlate recovery response measured by dark adaptation recovery time with drusen volume reduction measured by SD-OCT

What is the current status of trial NCT04735263?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2021-02-04. Estimated completion is 2028-01-01.

What conditions does trial NCT04735263 study?

This clinical trial studies the following conditions: Age-related Macular Degeneration.

What interventions are being tested in trial NCT04735263?

The interventions under investigation include: Atorvastatin 80mg (DRUG).

Who is sponsoring clinical trial NCT04735263?

This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04735263 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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