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NCT04752020 · ClinicalTrials.gov registry record · Early Phase 1
Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty
A Early Phase 1 study, sponsored by Massachusetts Eye and Ear Infirmary.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 25
- Enrollment target
NCT04752020: Completed Early Phase 1 study, sponsored by Massachusetts Eye and Ear Infirmary.
NCT04752020 is a Early Phase 1 study that has completed, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 25 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04752020, a Early Phase 1 study, has completed, sponsored by Massachusetts Eye and Ear Infirmary.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
This will be a prospective assessment of whether adjuvant Netarsudil use in patients undergoing Descemetorhexis without endothelial keratoplasty improves time to corneal clearance and post-operative central endothelial cell counts. The anticipated enrollment is 25 patients.
Primary Outcome
Corneal thickness on clinical examination and corneal topography
Interventions
- DRUG Netarsudil Ophthalmic
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2021-03-28 |
| Est. Completion | 2023-12-30 |
| Phase | Early Phase 1 |
What the finished NCT04752020 record still lists
NCT04752020 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 1 intervention - of which Netarsudil Ophthalmic is the first listed.
NCT04752020 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04752020 about?
NCT04752020 is a clinical study titled "Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty". This will be a prospective assessment of whether adjuvant Netarsudil use in patients undergoing Descemetorhexis without endothelial keratoplasty improves time to corneal clearance and post-operative central endothelial cell counts. The anticipated enrollment is 25 patients.
What is the current status of trial NCT04752020?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 25 participants. The study started on 2021-03-28. Estimated completion is 2023-12-30.
What interventions are being tested in trial NCT04752020?
The interventions under investigation include: Netarsudil Ophthalmic (DRUG).
Who is sponsoring clinical trial NCT04752020?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04752020's enrollment target sits among peer trials
25 1000th of 2000 higher than 965 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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