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NCT07318480 · ClinicalTrials.gov registry record · NA
Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder
A NA study of Cocaine Dependence and Cocaine Use Disorder, sponsored by Icahn School of Medicine at Mount Sinai.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT07318480: Recruiting NA study of Cocaine Dependence and Cocaine Use Disorder, sponsored by Icahn School of Medicine at Mount Sinai.
NCT07318480 is a NA study of Cocaine Dependence and Cocaine Use Disorder that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 120 participants, below the 295-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07318480, a NA study of Cocaine Dependence and Cocaine Use Disorder, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The researchers will test whether cognitively enhanced transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex can reduce craving in inpatients with cocaine use disorder. Neuroimaging before and after stimulation will establish the neural correlates of recovery and allow predictions of outcomes, which will be assessed throughout the study and one month after its completion. Results could pave the way towards development of a new self-administered intervention to reduce craving when it is needed the most, enhancing recovery real-time and in the natural environment in people with cocaine addiction as generalizable to other drugs of abuse and other disorders of self-control.
Primary Outcome
Neuroimaging - Measure of fMRI blood-oxygenation level dependent (BOLD) signal in the dorsolateral prefrontal cortex before and immediately after 5 weeks of tDCS.
Conditions Studied
Interventions
- DEVICE Transcranial Direct Current Stimulator (tDCS)
- BEHAVIORAL Cognitive Reappraisal Training
Study Locations (1)
New York
- Icahn School of Medicine at Mount Sinai - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2026-02-25 |
| Est. Completion | 2030-02 |
| Phase | NA |
What NCT07318480 shows while recruiting
NCT07318480 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 295-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (59% lower).
The record links to 3 conditions, with Cocaine Dependence appearing as the primary indexed condition, and to 2 interventions - of which Transcranial Direct Current Stimulator (tDCS) is the first listed.
NCT07318480 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT07318480 about?
NCT07318480 is a clinical study titled "Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder". The researchers will test whether cognitively enhanced transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex can reduce craving in inpatients with cocaine use disorder. Neuroimaging before and after stimulation will establish the neural correlates of recovery and allow...
What is the current status of trial NCT07318480?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2026-02-25. Estimated completion is 2030-02.
What conditions does trial NCT07318480 study?
This clinical trial studies the following conditions: Cocaine Dependence, Cocaine Use Disorder, Substance Use Disorder (SUD).
What interventions are being tested in trial NCT07318480?
The interventions under investigation include: Transcranial Direct Current Stimulator (tDCS) (DEVICE), Cognitive Reappraisal Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT07318480?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07318480 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cocaine Dependence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07318480's enrollment target sits among peer trials
120 15th of 38 higher than 23 of 38 other Cocaine Dependence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cocaine Dependence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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