GlaxoSmithKline
GlaxoSmithKline sponsors 1,345 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 1,130 completed. 486 of these trials are in Phase 3-4 (later-stage) and 791 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pulmonary Disease, Chronic Obstructive, with 30 trials.
Trial Pipeline
1,345 total, page 18 of 27
A 24-Week Study to Evaluate the Safety and Efficacy of ADVAIR DISKUS® Inhaler 250/50mcg Plus SPIRIVA HANDIHALER® Inhaler Versus SPIRIVA HANDIHALER® Inhaler Plus Placebo DISKUS® Inhaler in Subjects With Chronic Obstructive Pulmonary Disease (COPD).
NCT00784550
Dose Response of a Tubule Occlusion Agent
NCT01075256
Safety and Tolerability of Repeat Dosing of GSK233705/GW642444 in COPD
NCT00749411
A Pharmacokinetic Study to Evaluate TREXIMET in Adolescents With Migraine and Healthy Subjects Administered at Three Doses.
NCT00989625
An Imaging Study in Patients With Atherosclerosis Taking Rilapladib or Placebo for 12 Weeks
NCT00695305
A Study to Determine the Effect of Sumatriptan and Naproxen Sodium Combination Tablet, Sumatriptan Tablet, and Naproxen Sodium Tablet on Blood Pressure When Treating Migraine Headaches That Occur During a 6-month Period
NCT00792636
The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Toddlers
NCT00718666
Immunogenicity & Safety of GSK's Avian Flu Vaccine 1557484A Given to Adults Aged 18-64 Years
NCT00771615
Clinical Study of the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in People Aged 65 Years or Older
NCT00765076
Evaluation of the Safety and Immunogenicity of the Influenza Vaccine GSK2186877A in the Elderly
NCT00772889
A Study of the Effects of a New Antidepressant Treatment (GSK561679) in Females With Major Depressive Disorder
NCT00733980
Immunogenicity and Safety of GSK Biologicals' Influenza Vaccine Versus a Licensed Comparator in Children
NCT00764790
Evaluation of a New Anti-cancer Immunotherapy After Chemotherapy in Adult Patients With Acute Myeloid Leukemia (AML)
NCT00725283
Safety and Efficacy of GW685698X an Inhaled Corticosteroid Once Daily and Twice Daily for the Treatment of Asthma
NCT00766090
GSK1349572 Drug Interaction Study With Protease Inhibitors
NCT00774735
Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy
NCT00753688
GSK1349572 Drug Interaction Study With Etravirine
NCT00774111
Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors
NCT00732420
Trial to Evaluate the Efficacy of GSK Biologicals' Influenza Vaccine GSK2186877A in Adults 65 Year of Age and Older
NCT00753272
A Study in Healthy Volunteers of Single Doses of Orally Administered Investigational Product to Investigate Safety, Tolerability, and Pharmacokinecs.
NCT00783549
A Healthy Volunteer Pharmacokinetic Study of Single and Repeat Doses of SB-480848
NCT00743860
Effect of Orlistat in Body Composition
NCT00752726
A Bioavailability Study of GSK1363089 in Subjects With Solid Tumors
NCT00742261
A Study to Test How SB756050 Affects Subjects With Type 2 Diabetes Mellitus After 6 Days of Dosing.
NCT00733577
GSK1349572 Drug Interaction With Tenofovir
NCT00726336
Trial of Otelixizumab for Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-1
NCT00678886
Open-label Study to Investigate the Safety, PK, and Pharmacodynamics of GSK1120212 in Subjects With Solid Tumors or Lymphoma
NCT00687622
GSK706769/KALETRA Drug-drug Interaction Study
NCT00723775
Immunogenicity & Safety of GSK's Avian Flu Vaccine 1557484A Given to Adults Aged ≥18 Years
NCT00719043
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK1278863A in Healthy Subjects
NCT00750256
PAXIL CR Bioequivalence Study
NCT00749359
A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease
NCT00710684
Lamictal as Add-on Treatment for Bipolar I Disorder in Pediatric Patients
NCT00723450
The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Adolescents/Adults
NCT00715910
Study of Oral Topotecan With Bevacizumab for Recurrent Small Cell Lung Cancer
NCT00698516
A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam.
NCT00929370
An Extension to Study MD7108240
NCT00733304
Phase I Open-Label, Dose-Escalation Study of GSK1059615 in Patients With Solid Tumors or Lymphoma
NCT00695448
Combination Study Of SB-485232 (Interleukin 18) And Doxil For Advanced Stage Epithelial Ovarian Cancer
NCT00659178
Study to Evaluate SC Route of Administration of Ofatumumab in RA Patients
NCT00686868
Safety and Immune Response Study of GSK Biologicals' Influenza Virus Vaccine 1388442A Compared With Fluarix
NCT00693706
A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis
NCT00682643
Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes
NCT00708305
Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures
NCT00678587
Lapatinib + Vinorelbine in ErbB2 Overexpressing, First or Second Line Metastatic Breast Cancer Subjects
NCT00709618
Dose-Ranging Study Of GSK233705B In Subjects With Chronic Obstructive Pulmonary Disease (COPD)
NCT00676052
GSK706769 Repeat Dose Study
NCT00711386
Repeat Dose Food Effect Study of GSK256073F in Healthy Adult Subjects
NCT00808093
An Open-label, Randomized, 3-period Crossover Study to Evaluate Sumatriptan Pharmacokinetics for a TREXIMA™ (Sumatriptan Succinate / Naproxen Sodium) Tablet Followed by IMITREX® (Sumatriptan Succinate)
NCT00875784
A Study With Darapladib to Collect Tolerability Information
NCT00704431
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 440 |
| Phase 2 | 351 |
| Phase 3 | 377 |
| Phase 4 | 109 |
Therapeutic Areas
What the Pipeline for GlaxoSmithKline Shows
According to the ClinicalTrials.gov registry, GlaxoSmithKline is linked to 1,345 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 1,130 are already marked complete, representing roughly 84% of the total.
The phase mix for GlaxoSmithKline reports 486 late-stage studies (Phase 3 and Phase 4 combined) and 791 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for GlaxoSmithKline is Pulmonary Disease, Chronic Obstructive with 30 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.