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NCT00686868 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate SC Route of Administration of Ofatumumab in RA Patients
A Phase 1 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 1
- Development phase
- 35
- Enrollment target
NCT00686868: Completed Phase 1 study, sponsored by GlaxoSmithKline.
NCT00686868 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 35 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00686868, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 35 participants
- Enrollment target
Study Summary
This study will examine the safety and tolerability, PK and PD of subcutaneously administered GSK1841157 in patients with RA on stable dose Methotrexate. The study comprises a single dose escalation/de-escalation phase to investigate the minimal efficacious dose based on PD markers with an acceptable safety profile.
Interventions
- OTHER placebo
- DRUG ofatumumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2008-06-13 |
| Est. Completion | 2011-05-02 |
| Phase | Phase 1 |
What the finished NCT00686868 record still lists
NCT00686868 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% lower).
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT00686868 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00686868 about?
NCT00686868 is a clinical study titled "Study to Evaluate SC Route of Administration of Ofatumumab in RA Patients". This study will examine the safety and tolerability, PK and PD of subcutaneously administered GSK1841157 in patients with RA on stable dose Methotrexate. The study comprises a single dose escalation/de-escalation phase to investigate the minimal efficacious dose based on PD markers with an acceptabl...
What is the current status of trial NCT00686868?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2008-06-13. Estimated completion is 2011-05-02.
What interventions are being tested in trial NCT00686868?
The interventions under investigation include: placebo (OTHER), ofatumumab (DRUG).
Who is sponsoring clinical trial NCT00686868?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00686868's enrollment target sits among peer trials
35 1258th of 2000 higher than 728 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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