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NCT00659178 · ClinicalTrials.gov registry record · Phase 1
Combination Study Of SB-485232 (Interleukin 18) And Doxil For Advanced Stage Epithelial Ovarian Cancer
A Phase 1 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
NCT00659178: Completed Phase 1 study, sponsored by GlaxoSmithKline.
NCT00659178 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00659178, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
The purpose of this study is to identify a dose of SB-485232 which is safe, tolerable and biologically active when used in combination with pegylated liposomal doxorubicin (Doxil) in patients with epithelial ovarian cancer. This study will use a standard treatment regimen of pegylated liposomal doxorubicin (Doxil) in combination with rising doses of SB-485232. The dose selected from this study will be used in a future studies to evaluate the efficacy of this combination.
Interventions
- DRUG SB-485232 (interleukin 18), pegylated liposomal doxorubicin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2008-06-18 |
| Est. Completion | 2011-02-18 |
| Phase | Phase 1 |
What the finished NCT00659178 record still lists
NCT00659178 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 1 intervention - of which SB-485232 (interleukin 18), pegylated liposomal doxorubicin is the first listed.
NCT00659178 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00659178 about?
NCT00659178 is a clinical study titled "Combination Study Of SB-485232 (Interleukin 18) And Doxil For Advanced Stage Epithelial Ovarian Cancer". The purpose of this study is to identify a dose of SB-485232 which is safe, tolerable and biologically active when used in combination with pegylated liposomal doxorubicin (Doxil) in patients with epithelial ovarian cancer. This study will use a standard treatment regimen of pegylated liposomal doxo...
What is the current status of trial NCT00659178?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2008-06-18. Estimated completion is 2011-02-18.
What interventions are being tested in trial NCT00659178?
The interventions under investigation include: SB-485232 (interleukin 18), pegylated liposomal doxorubicin (DRUG).
Who is sponsoring clinical trial NCT00659178?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00659178's enrollment target sits among peer trials
15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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