Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00682643 · ClinicalTrials.gov registry record · Phase 4

A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis

A Phase 4 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 4
Development phase
550
Enrollment target

NCT00682643: Completed Phase 4 study, sponsored by GlaxoSmithKline.

NCT00682643 is a Phase 4 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 550 participants, roughly in line with the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00682643, a Phase 4 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 4
Development phase
550 participants
Enrollment target

Study Summary

The purpose of this study is to assess long-term ocular safety of fluticasone furoate nasal spray in adult and adolescent subjects diagnosed with perennial allergic rhinitis.

Primary Outcome

An event for P (opacity in the lens positioned just anterior to the posterior lens capsule and characterized by the posterior migration of lens epithelial cells from the lens bow) is defined as an increase of \>=0.3 from baseline in Lens Opacities Classification System, Version III (LOCS III; system used for the grading and comparison of cataract severity and type based on standard color photographic transparencies) grade for P (range=0.1 \[lens clear\] to 5.9 \[lens unclear\]), in either eye. D

Interventions

  • DRUG fluticasone furoate nasal spray
  • DRUG vehicle placebo nasal spray

Trial Details

FieldValue
Enrollment Target 550 participants
Start Date 2008-06
Est. Completion 2011-02
Phase Phase 4
GlaxoSmithKline

1,345 total trials

What the finished NCT00682643 record still lists

NCT00682643 is an interventional study that assigns participants to a tested intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target.

The record links to 0 conditions, and to 2 interventions - of which fluticasone furoate nasal spray is the first listed.

NCT00682643 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00682643 about?

NCT00682643 is a clinical study titled "A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis". The purpose of this study is to assess long-term ocular safety of fluticasone furoate nasal spray in adult and adolescent subjects diagnosed with perennial allergic rhinitis.

What is the current status of trial NCT00682643?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 550 participants. The study started on 2008-06. Estimated completion is 2011-02.

What interventions are being tested in trial NCT00682643?

The interventions under investigation include: fluticasone furoate nasal spray (DRUG), vehicle placebo nasal spray (DRUG).

Who is sponsoring clinical trial NCT00682643?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00682643's enrollment target sits among peer trials

550 152nd of 2000 higher than 1,848 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01852448 · 550 participants

    Genetics of Insulin and Incretins in Cystic Fibrosis

  • NCT02995252 · 550 participants

    The HOPE Study: Characterizing Patients With Hepatitis B and C

  • NCT03474913 · 550 participants

    Upright MRI for Prostate Cancer Screening

  • NCT04761120 · 550 participants

    Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00682643, the US trial registry maintained by the National Library of Medicine. NCT00682643 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.