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NCT01075256 · ClinicalTrials.gov registry record · Phase 4
Dose Response of a Tubule Occlusion Agent
A Phase 4 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 4
- Development phase
- 195
- Enrollment target
NCT01075256: Completed Phase 4 study, sponsored by GlaxoSmithKline.
NCT01075256 is a Phase 4 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 195 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01075256, a Phase 4 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 195 participants
- Enrollment target
Study Summary
To evaluate the efficacy of two different concentrations of a tubule occlusion agent - calcium sodium phosphosilicate in treatment of dentine hypersensitivity
Primary Outcome
Response to a constant jet of air applied to a hypersensitive tooth was evaluated using a 100 millimeter (mm) VAS pain response scale. According to this analog scale, pain response for stimulated tooth ranged from 0 (no pain) to 100 (intense pain). Change from baseline in pain response was calculated using VAS score and a change of greater than 25 mm in VAS indicates potential relevant clinical significance of treatment.
Interventions
- DEVICE 5% calcium sodium phosphosilicate toothpaste
- DEVICE 7.5% calcium sodium phosphosilicate toothpaste
- DEVICE Placebo toothpaste
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 195 participants |
| Start Date | 2008-12 |
| Est. Completion | 2009-03 |
| Phase | Phase 4 |
What the finished NCT01075256 record still lists
NCT01075256 is an interventional study that assigns participants to a tested intervention. The registered 195 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 3 interventions - of which 5% calcium sodium phosphosilicate toothpaste is the first listed.
NCT01075256 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01075256 about?
NCT01075256 is a clinical study titled "Dose Response of a Tubule Occlusion Agent". To evaluate the efficacy of two different concentrations of a tubule occlusion agent - calcium sodium phosphosilicate in treatment of dentine hypersensitivity
What is the current status of trial NCT01075256?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 195 participants. The study started on 2008-12. Estimated completion is 2009-03.
What interventions are being tested in trial NCT01075256?
The interventions under investigation include: 5% calcium sodium phosphosilicate toothpaste (DEVICE), 7.5% calcium sodium phosphosilicate toothpaste (DEVICE), Placebo toothpaste (DEVICE).
Who is sponsoring clinical trial NCT01075256?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01075256's enrollment target sits among peer trials
195 450th of 2000 higher than 1,550 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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