EMD Serono Research & Development Institute
EMD Serono Research & Development Institute sponsors 81 registered US clinical trials on ClinicalTrials.gov, 9 of them currently recruiting, and 40 completed. 17 of these trials are in Phase 3-4 (later-stage) and 58 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Solid Tumor, with 4 trials.
Trial Pipeline
81 total, page 2 of 2
Study of Avelumab-M3814 Combinations
NCT03724890
M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)
NCT03631706
Tepotinib Hepatic Impairment Trial
NCT03546608
Phase I/II Study of Avelumab in Pediatric Cancer Participants
NCT03451825
First-in-Human Study of MS201408-0005A as Single Agent and in Combinations
NCT03306420
Phase IIb Study of Evobrutinib in Subjects With Rheumatoid Arthritis
NCT03233230
M3541 in Combination With Radiotherapy in Solid Tumors
NCT03225105
Retrospective Study to Determine Effect of Rebif and Tecfidera on Infections and Lymphocytes
NCT03284970
M8891 First in Human in Solid Tumors
NCT03138538
Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)
NCT03116971
A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12)
NCT02994953
Efficacy and Safety of Atacicept in IgA Nephropathy
NCT02808429
A Phase II Study of M2951 in SLE
NCT02975336
Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis
NCT02784106
Abituzumab in SSc-ILD
NCT02745145
First-in-Human Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of VX-984 in Combination With Chemotherapy
NCT02644278
Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)
NCT02625623
Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)
NCT02625610
MSC2364447C Phase 1b in Systemic Lupus Erythematosus
NCT02537028
Avelumab in First-line NSCLC (JAVELIN Lung 100)
NCT02576574
Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy
NCT02516813
MSB0011359C (M7824) in Metastatic or Locally Advanced Solid Tumors
NCT02517398
Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200)
NCT02395172
First in Human Study of M4344 in Participants With Advanced Solid Tumors
NCT02278250
Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)
NCT02155647
A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee
NCT01919164
Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)
NCT01772004
M6620 First in Human Study
NCT02157792
Oral Cladribine in Early Multiple Sclerosis (MS)
NCT00725985
CLARITY Extension Study
NCT00641537
A Phase 2 Study of Cladribine Add-on to Interferon-beta (IFN-beta) Therapy in Multiple Sclerosis (MS) Subjects With Active Disease (ONWARD)
NCT00436826
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 36 |
| Phase 2 | 22 |
| Phase 3 | 16 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for EMD Serono Research & Development Institute Shows
According to the ClinicalTrials.gov registry, EMD Serono Research & Development Institute is linked to 81 US clinical trials across every stage of research activity. Of those, 9 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 40 are already marked complete, representing roughly 49% of the total.
The phase mix for EMD Serono Research & Development Institute reports 17 late-stage studies (Phase 3 and Phase 4 combined) and 58 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for EMD Serono Research & Development Institute is Advanced Solid Tumor with 4 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.