EMD Serono Research & Development Institute

81 total trials 9 currently recruiting 40 completed

EMD Serono Research & Development Institute sponsors 81 registered US clinical trials on ClinicalTrials.gov, 9 of them currently recruiting, and 40 completed. 17 of these trials are in Phase 3-4 (later-stage) and 58 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Solid Tumor, with 4 trials.

Trial Pipeline

81 total, page 2 of 2

COMPLETED Phase 1

Study of Avelumab-M3814 Combinations

NCT03724890

COMPLETED Phase 3

M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)

NCT03631706

COMPLETED Phase 1

Tepotinib Hepatic Impairment Trial

NCT03546608

TERMINATED Phase 1

Phase I/II Study of Avelumab in Pediatric Cancer Participants

NCT03451825

TERMINATED Phase 1

First-in-Human Study of MS201408-0005A as Single Agent and in Combinations

NCT03306420

COMPLETED Phase 2

Phase IIb Study of Evobrutinib in Subjects With Rheumatoid Arthritis

NCT03233230

TERMINATED Phase 1

M3541 in Combination With Radiotherapy in Solid Tumors

NCT03225105

COMPLETED

Retrospective Study to Determine Effect of Rebif and Tecfidera on Infections and Lymphocytes

NCT03284970

TERMINATED Phase 1

M8891 First in Human in Solid Tumors

NCT03138538

TERMINATED Phase 1

Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)

NCT03116971

TERMINATED Phase 1

A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12)

NCT02994953

TERMINATED Phase 2

Efficacy and Safety of Atacicept in IgA Nephropathy

NCT02808429

TERMINATED Phase 2

A Phase II Study of M2951 in SLE

NCT02975336

COMPLETED Phase 2

Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis

NCT02784106

TERMINATED Phase 2

Abituzumab in SSc-ILD

NCT02745145

COMPLETED Phase 1

First-in-Human Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of VX-984 in Combination With Chemotherapy

NCT02644278

COMPLETED Phase 3

Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)

NCT02625623

COMPLETED Phase 3

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

NCT02625610

COMPLETED Phase 1

MSC2364447C Phase 1b in Systemic Lupus Erythematosus

NCT02537028

COMPLETED Phase 3

Avelumab in First-line NSCLC (JAVELIN Lung 100)

NCT02576574

COMPLETED Phase 1

Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy

NCT02516813

COMPLETED Phase 1

MSB0011359C (M7824) in Metastatic or Locally Advanced Solid Tumors

NCT02517398

COMPLETED Phase 3

Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200)

NCT02395172

COMPLETED Phase 1

First in Human Study of M4344 in Participants With Advanced Solid Tumors

NCT02278250

COMPLETED Phase 2

Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)

NCT02155647

COMPLETED Phase 2

A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee

NCT01919164

COMPLETED Phase 1

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

NCT01772004

COMPLETED Phase 1

M6620 First in Human Study

NCT02157792

COMPLETED Phase 3

Oral Cladribine in Early Multiple Sclerosis (MS)

NCT00725985

COMPLETED Phase 3

CLARITY Extension Study

NCT00641537

COMPLETED Phase 2

A Phase 2 Study of Cladribine Add-on to Interferon-beta (IFN-beta) Therapy in Multiple Sclerosis (MS) Subjects With Active Disease (ONWARD)

NCT00436826

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What the Pipeline for EMD Serono Research & Development Institute Shows

According to the ClinicalTrials.gov registry, EMD Serono Research & Development Institute is linked to 81 US clinical trials across every stage of research activity. Of those, 9 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 40 are already marked complete, representing roughly 49% of the total.

The phase mix for EMD Serono Research & Development Institute reports 17 late-stage studies (Phase 3 and Phase 4 combined) and 58 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for EMD Serono Research & Development Institute is Advanced Solid Tumor with 4 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.