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NCT03306420 · ClinicalTrials.gov registry record · Phase 1

First-in-Human Study of MS201408-0005A as Single Agent and in Combinations

A Phase 1 study, sponsored by EMD Serono Research & Development Institute.

Terminated
Registry status
Phase 1
Development phase
15
Enrollment target

NCT03306420 is a Phase 1 study that was terminated before completion, run by EMD Serono Research & Development Institute. The registered enrollment target is 15 participants.

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The verdict

NCT03306420, a Phase 1 study, was terminated before completion, sponsored by EMD Serono Research & Development Institute.

TERMINATED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

This is a Phase I, open-label study to determine the safety, tolerability, pharmacokinetic (PK), pharmacodynamics (PD), and preliminary antitumor activity of MS201408-0005A as single agent (Part IA only) and in combination with MS201408-0005C or MS201408-0005B (Part IB, Part IC).

Interventions

  • DRUG M4112

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2017-10-03
Est. Completion 2019-01-14
Phase Phase 1

What the Registry Record Tells You About NCT03306420

The ClinicalTrials.gov registry entry for NCT03306420 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is EMD Serono Research & Development Institute, which has 81 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which M4112 is the first listed.

NCT03306420 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03306420 about?

NCT03306420 is a clinical study titled "First-in-Human Study of MS201408-0005A as Single Agent and in Combinations". This is a Phase I, open-label study to determine the safety, tolerability, pharmacokinetic (PK), pharmacodynamics (PD), and preliminary antitumor activity of MS201408-0005A as single agent (Part IA only) and in combination with MS201408-0005C or MS201408-0005B (Part IB, Part IC).

What is the current status of trial NCT03306420?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2017-10-03. Estimated completion is 2019-01-14.

What interventions are being tested in trial NCT03306420?

The interventions under investigation include: M4112 (DRUG).

Who is sponsoring clinical trial NCT03306420?

This trial is sponsored by EMD Serono Research & Development Institute, which has 81 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.