Amylyx Pharmaceuticals
Trial Pipeline
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
NCT06665165
Avexitide for Treatment of Post-Bariatric Hypoglycemia
NCT06747468
AMX0035 and Progressive Supranuclear Palsy
NCT06122662
AMX0035 in Adult Patients With Wolfram Syndrome
NCT05676034
Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment
NCT05021536
A Compassionate Use Protocol of AMX0035 for Treatment of Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT04516096
Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease
NCT03533257
Open Label Extension Study of AMX0035 in Patients With ALS
NCT03488524
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 3 | 2 |
Therapeutic Areas
What the Pipeline for Amylyx Pharmaceuticals Shows
According to the ClinicalTrials.gov registry, Amylyx Pharmaceuticals is linked to 8 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting — about 13% of the sponsor's indexed portfolio — and 3 are already marked complete, representing roughly 38% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Amylyx Pharmaceuticals reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 6 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Amylyx Pharmaceuticals is Amyotrophic Lateral Sclerosis with 3 linked trials, and 8 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.