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NCT02625610 · ClinicalTrials.gov registry record · Phase 3

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

A Phase 3 study, sponsored by EMD Serono Research & Development Institute.

Completed
Registry status
Phase 3
Development phase
499
Enrollment target

NCT02625610: Completed Phase 3 study, sponsored by EMD Serono Research & Development Institute.

NCT02625610 is a Phase 3 study that has completed, run by EMD Serono Research & Development Institute. The registered enrollment target is 499 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02625610, a Phase 3 study, has completed, sponsored by EMD Serono Research & Development Institute.

COMPLETED
Registry status
Phase 3
Development phase
499 participants
Enrollment target

Study Summary

The purpose of this study was to demonstrate superiority of treatment with avelumab versus continuation of first-line chemotherapy.

Primary Outcome

Overall Survival was defined as the time from randomization to the date of death due to any cause. For participants who were still alive at the time of data analysis or who were lost to follow-up, OS time was censored at the date of last contact. OS was measured using Kaplan-Meier (KM) estimates.

Interventions

  • DRUG Capecitabine
  • DRUG Leucovorin
  • DRUG Oxaliplatin
  • DRUG 5-Fluorouracil
  • DRUG Avelumab

Trial Details

FieldValue
Enrollment Target 499 participants
Start Date 2015-12-24
Est. Completion 2021-06-03
Phase Phase 3

What the finished NCT02625610 record still lists

NCT02625610 is an interventional study that assigns participants to a tested intervention. The registered 499 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (35% lower).

The record links to 0 conditions, and to 5 interventions - of which Capecitabine is the first listed.

NCT02625610 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02625610 about?

NCT02625610 is a clinical study titled "Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)". The purpose of this study was to demonstrate superiority of treatment with avelumab versus continuation of first-line chemotherapy.

What is the current status of trial NCT02625610?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 499 participants. The study started on 2015-12-24. Estimated completion is 2021-06-03.

What interventions are being tested in trial NCT02625610?

The interventions under investigation include: Capecitabine (DRUG), Leucovorin (DRUG), Oxaliplatin (DRUG), 5-Fluorouracil (DRUG), Avelumab (DRUG).

Who is sponsoring clinical trial NCT02625610?

This trial is sponsored by EMD Serono Research & Development Institute, which has 81 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02625610's enrollment target sits among peer trials

499 775th of 2000 higher than 1,226 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02625610, the US trial registry maintained by the National Library of Medicine. NCT02625610 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.