Eli Lilly and Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Eli Lilly and Company sits in the top decile of US sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count).

1,341 total trials 124 currently recruiting 1029 completed early-phase tilt top decile by trial count

Eli Lilly and Company: 1,341 sponsored US clinical trials, 124 recruiting.

Eli Lilly and Company sponsors 1,341 registered US clinical trials on ClinicalTrials.gov, 124 of them currently recruiting, and 1,029 completed. 459 of these trials are in Phase 3-4 (later-stage) and 861 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 55 trials.

Top-decile sponsor footprint

Eli Lilly and Company ranks in the top decile of sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 67/100

1,029 of 1,131 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,341 total, page 22 of 27

COMPLETED Phase 4

Treatment of ADHD With Atomoxetine in Children & Adolescents With ADHD & Comorbid Dyslexia

NCT00607919

COMPLETED Phase 2

A Study of an Experimental Chemotherapy Combination to Treat Hormone Refractory Prostate Cancer

NCT00642018

COMPLETED Phase 3

Effect of LY450139 on the Long Term Progression of Alzheimer's Disease

NCT00594568

COMPLETED Phase 2

A Study of LY2181308 Sodium in Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT00620321

COMPLETED Phase 2

Study of Enzastaurin With 5-Fluorouracil/Leucovorin (5-FU/LV) Plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colon Cancer

NCT00612586

COMPLETED Phase 1

A Phase 1 Study in Patients With Solid Tumors

NCT01215916

COMPLETED Phase 2

Study of IMC-1121B (Ramucirumab) in Participants With Liver Cancer Who Have Not Previously Been Treated With Chemotherapy

NCT00627042

COMPLETED Phase 1

A Dose-Escalation Study in Participants With Advanced Cancer

NCT01524224

COMPLETED

Safety Study of Atomoxetine and Cerebrovascular Outcomes

NCT00634439

COMPLETED Phase 3

Study of the Experience of Patients With Osteoporosis Using the Forteo B Pen to Self Administer Once Daily Teriparatide Therapy

NCT00577863

COMPLETED Phase 2

A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers

NCT00414960

COMPLETED Phase 3

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes Taking Oral Diabetes Medicines and Exenatide

NCT00560417

COMPLETED Phase 2

A Study of Ramucirumab in Participants With Metastatic Renal Cell Carcinoma

NCT00515697

COMPLETED Phase 4

A Study Using Imaging Technology to Measure Changes in Bone Structure After Treatment With Teriparatide

NCT00557310

COMPLETED Phase 2

A Study of IMC-1121B (Ramucirumab) With or Without Dacarbazine in Metastatic Malignant Melanoma

NCT00533702

COMPLETED Phase 1

A Study of LY2090314 in Patients With Advanced or Metastatic Cancer

NCT01287520

COMPLETED Phase 2

Trial of Enzastaurin and Bevacizumab in Participants With Recurrent Malignant Gliomas

NCT00586508

COMPLETED Phase 2

A Study for Patients With Non-Hodgkin's Lymphomas

NCT00542919

TERMINATED Phase 2

Trial of Paclitaxel, Bevacizumab, and Enzastaurin Versus Paclitaxel, Bevacizumab and Placebo for Breast Cancer

NCT00536939

COMPLETED Phase 2

Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been Previously Treated With Chemotherapy

NCT00533429

COMPLETED Phase 2

A Study of the Pharmacokinetics of Testosterone Metered Dose (MD)-Lotion Formulations

NCT00857961

COMPLETED Phase 2

A Study of Pemetrexed in Children With Recurrent Cancer

NCT00520936

COMPLETED Phase 2

Study of Enzastaurin Versus Placebo With Pemetrexed for Participants With Advanced or Metastatic Lung Cancer

NCT00530621

COMPLETED Phase 4

A Study Comparing Duloxetine and Placebo in Assessing Energy and Vitality in Major Depressive Disorder (MDD) Patients

NCT00536471

COMPLETED Phase 4

Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes

NCT00510276

COMPLETED Phase 2

A Study of LY573636-Sodium in the Treatment of Patients With Metastatic Soft Tissue Sarcoma

NCT00490451

COMPLETED Phase 3

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes on Anti-Hyperglycemic Medications (IOPE)

NCT00510952

COMPLETED Phase 2

Study With IMC-A12 (Cixutumumab) in Patients Who Have Not Previously Been Treated With Chemotherapy With Metastatic Prostate Cancer

NCT00520481

COMPLETED Phase 3

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes (IOOY)

NCT00494013

COMPLETED Phase 2

Open-Label Study of Duloxetine in the Treatment of Children and Adolescents With Major Depressive Disorder

NCT00529789

COMPLETED Phase 1

A Study for Participants With Advanced Cancer

NCT01214629

COMPLETED Phase 2

A Phase 2 Study With Enzastaurin Plus Chemotherapy or Placebo Plus Chemotherapy for Prostate Cancer Patients

NCT00466440

COMPLETED Phase 3

Comparison of Two Basal Insulin Therapies for Patients With Type 1 Diabetes

NCT00487240

COMPLETED Phase 2

Study Using IMC-A12 (Cixutumumab) With or Without Cetuximab in Participants With Metastatic Colorectal Cancer Who Have Failed a Treatment Regimen That Consisted of a Prior Anti-EGFR Therapy

NCT00503685

COMPLETED Phase 2

A Study of Enzastaurin in Participants With Follicular Lymphoma

NCT00475644

COMPLETED Phase 1

A Study of Enzastaurin and Erlotinib in Participants With Solid Tumors and Lung Cancer

NCT00452413

COMPLETED Phase 2

A Study of Participants With Lymphoma Who Take R-CHOP and Enzastaurin Compared to Participants Who Take R-CHOP Only

NCT00451178

COMPLETED Phase 1

A Study of Pemetrexed Plus Carboplatin, or Pemetrexed Plus Cisplatin With Radiation Therapy Followed by Pemetrexed in Patients With Inoperable Non-Small-Cell Lung Cancer

NCT00482014

COMPLETED Phase 1

A Study of Enzastaurin in Patients With Leukemia

NCT00452257

COMPLETED Phase 2

A Study of Irinotecan Plus Cetuximab With or Without Enzastaurin in Participants With Colorectal Cancer

NCT00437268

COMPLETED Phase 3

Duloxetine vs. Placebo in the Treatment of Osteoarthritis Knee Pain

NCT00433290

COMPLETED Phase 2

A Study of Chemotherapy Treatment for Patients With Ovarian Cancer

NCT00428610

COMPLETED Phase 3

Evaluate the Efficacy and Safety of Insulin Compared to Glargine in Patients With Type 2 Diabetes

NCT00437112

COMPLETED

An Observational Study of the Ethnic Impact of Patients Undergoing Second (2nd) Line Treatment for Non-Small Cell Lung Cancer Using Pemetrexed

NCT00497770

TERMINATED Phase 2

Pemetrexed and Gemcitabine Every 14 Days Versus Every 21 Days in Advanced Non Small Cell Lung Cancer

NCT00383331

COMPLETED Phase 1

A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas

NCT01445119

COMPLETED Phase 2

Phase 2 Trial of Enzastaurin in Prostate Cancer in Participants Who Have Had Hormonal and Chemotherapy

NCT00428714

COMPLETED Phase 1

Safety and Tolerability of IC83/LY2603618 Administered After Pemetrexed 500 mg/m2 Every 21 Days in Patients With Cancer

NCT00415636

COMPLETED Phase 2

Evaluation of Enzastaurin in the Treatment of Persistent or Recurrent Ovarian or Primary Peritoneal Cancer

NCT00420381

COMPLETED Phase 2

A Study for Participants With Major Depression

NCT00420004

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Phase Distribution

PhaseTrial count
Phase 1 517
Phase 2 344
Phase 3 368
Phase 4 91

What is open in the Eli Lilly and Company pipeline

124 recruiting of 1,341 indexed (9% open); 1,029 completed (77%).

Phase mix: 459 late (III/IV) vs 861 early (I/II) (early-phase heavy).

Top condition: Healthy (55 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Eli Lilly and Company: open-pipeline peers nationwide

Peers matched on 1,341 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share Eli Lilly and CompanyGlaxoSmithKlineUniversity of MichiganNovartis PharmaceuticalsAstraZenecaShionogiUniversity of KentuckyUniversity of VermontLahey Clinic
Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,341 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this Eli Lilly and Company page

1,341 registered trials is a research-attention snapshot, not an endorsement of Eli Lilly and Company or any single study.

  • 124 of Eli Lilly and Company's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition Eli Lilly and Company studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Eli Lilly and Company pipeline card: 1,341 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.