Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00529789 · ClinicalTrials.gov registry record · Phase 2

Open-Label Study of Duloxetine in the Treatment of Children and Adolescents With Major Depressive Disorder

A Phase 2 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 2
Development phase
72
Enrollment target

NCT00529789: Completed Phase 2 study, sponsored by Eli Lilly and Company.

NCT00529789 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 72 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (46% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00529789, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 2
Development phase
72 participants
Enrollment target

Study Summary

The primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition. Whether duloxetine once daily orally is tolerated and safe, in children (aged 7 through 11 years) and adolescents (aged 12 through 17 years) with Major Depressive Disorder.

Primary Outcome

Emergence of Any Suicidal Ideation: Item 13 of Children's Depression Rating Scale-Revised (CDRS-R) has possible scores of 1 (no thoughts of suicide) to 7 (contemplation of suicide). Emergence of suicidal ideation was defined as an increase in severity of suicidal ideation for those patients who did not have suicidal ideation at baseline (Week 0).

Interventions

  • DRUG duloxetine

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2007-08
Est. Completion 2008-09
Phase Phase 2
Eli Lilly and Company

1,341 total trials

What the finished NCT00529789 record still lists

NCT00529789 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (46% lower).

The record links to 0 conditions, and to 1 intervention - of which duloxetine is the first listed.

NCT00529789 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00529789 about?

NCT00529789 is a clinical study titled "Open-Label Study of Duloxetine in the Treatment of Children and Adolescents With Major Depressive Disorder". The primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition. Whether duloxetine once daily orally is tolerated and safe, in children (aged 7 through 11 years) and adolescents (aged 12 through 17 years)...

What is the current status of trial NCT00529789?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2007-08. Estimated completion is 2008-09.

What interventions are being tested in trial NCT00529789?

The interventions under investigation include: duloxetine (DRUG).

Who is sponsoring clinical trial NCT00529789?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00529789's enrollment target sits among peer trials

72 925th of 2000 higher than 1,065 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02359253 · 72 participants · NA

    Robot Aided Rehabilitation - Intervention

  • NCT02962661 · 72 participants · Phase 1

    Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines

  • NCT03113643 · 72 participants · Phase 1

    SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

  • NCT03187535 · 72 participants · NA

    Effect of TEAS on PONV After Spinal Surgery

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00529789, the US trial registry maintained by the National Library of Medicine. NCT00529789 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.