Duke University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).

1,725 total trials 187 currently recruiting 1244 completed early-phase tilt top decile by trial count

Duke University: 1,725 sponsored US clinical trials, 187 recruiting.

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Top-decile sponsor footprint

Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,725 total, page 8 of 35

COMPLETED Phase 2

REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant

NCT05733286

COMPLETED

Infection Watch Study

NCT04623047

COMPLETED

Energy Needs and Nutritional Status of Adolescent Girls

NCT06601959

COMPLETED NA

LowCostomy: Dedicated Toward Creating a High-quality, Low-cost Colostomy Appliance for Those in Sub-Saharan Africa

NCT05824351

COMPLETED NA

Optimizing In-hospital Use of Evidence-based Therapies for Patients With Cardio-Renal-Metabolic Disease

NCT05781334

COMPLETED Phase 1

Ketone Pharmacokinetic Study in HFrEF

NCT05757193

COMPLETED NA

Start the Conversation: Evaluating Implementation of a Multi-level PrEP Initiative for Black Cisgender Women in Nola

NCT05909176

COMPLETED NA

Modeling Organ Motion During Abdominal Imaging in Healthy Volunteers

NCT05674851

COMPLETED

Improving Screening and Therapy for Hispanic/Latinx at Risk for CKD

NCT05734989

COMPLETED NA

Healthy Me: A Program for Older Women

NCT03843190

TERMINATED

Effect of Corticosteroid Injections on Blood Glucose

NCT05048264

COMPLETED NA

Decision Making Support for Parents and Caregivers

NCT05733975

COMPLETED NA

The TALK for Black Male Adolescent Sexual Health

NCT05746585

COMPLETED NA

Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 1)

NCT05801120

COMPLETED NA

Five Session Unified Protocol for Older Adults With Emotional Distress and Reduced Mobility

NCT04837521

COMPLETED Phase 1

External Body Pressure in Heart Failure With Preserved Ejection Fraction

NCT05764564

COMPLETED Phase 4

ESP Block for Post Cesarean Analgesia

NCT05664958

COMPLETED NA

Brief Suicide Intervention for Youth in Juvenile Detention Settings

NCT05225103

COMPLETED

You and Me Healthy: Test to Treat

NCT07126392

COMPLETED NA

Food as Medicine Project

NCT05926193

COMPLETED Phase 4

Regional Anesthesia Following Pediatric Cardiac Surgery

NCT05688670

COMPLETED NA

Gerofit Exercise Intervention for Older Adults With Sickle Cell Disease (SICKLE-FIT Study)

NCT05714098

COMPLETED NA

Safety and Feasibility of tDCS to Enhance Auditory Rehabilitation in Cochlear Implant Recipients

NCT04908631

COMPLETED NA

Generating Evidence in ECMO Ventilation Strategies

NCT05708365

COMPLETED

IL13 Signaling in Allergic Asthma

NCT05478824

TERMINATED NA

African American Resilient Caregivers

NCT05711979

COMPLETED NA

Adolescents and Young Adults (AYAs) With Advanced Cancer

NCT05593016

COMPLETED NA

Engaging African American Older Adults With Arthritis in a Physical Activity Intervention

NCT05652413

COMPLETED NA

Personalized Nutrition Delivery to Improve Resilience in Older Adult Trauma Patients

NCT05544162

COMPLETED Early Phase 1

Stress Management Toolkit for People Living With Dementia and Their Care Partners

NCT05465551

COMPLETED NA

Transcutaneous Electrical Nerve Stimulation During Outpatient Endometrial Biopsy

NCT05472740

COMPLETED NA

Virtual Care to Improve Heart Failure Outcomes (VITAL-HF)

NCT05602454

COMPLETED NA

Survivorship Post-HCT Optimization Program

NCT05238376

COMPLETED NA

Systematic Evaluation of VNS Parameters

NCT05395026

COMPLETED

Prospective Low Dose CT for Total Shoulder Arthroplasty/Reverse Shoulder Arthroplasty

NCT05350319

TERMINATED NA

Automated Applanation Tonometry

NCT05235321

TERMINATED

Hearts of Athletes

NCT04736004

COMPLETED

Remote Monitoring of Surgical Patients Through VALIDIC

NCT05486962

COMPLETED NA

ABC Mental Health: A Behavioral Study of K-12 Teachers and School Staff

NCT05574764

COMPLETED NA

Comprehensive Adaptive Multisite Prevention of University Student Suicide

NCT04707066

COMPLETED NA

Lymph Drainage in Heart Failure

NCT05240638

COMPLETED NA

Sustainable Habits for Encouraging Even Teen Sleep

NCT05378373

COMPLETED NA

Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2

NCT05473585

COMPLETED

Sleep and IR in Transgender Adolescents

NCT05489159

COMPLETED NA

Feasibility Study of a Mobile Digital Personal Health Record for Family-Centered Care Coordination for Children and Youth With Special Healthcare Needs

NCT05513235

COMPLETED

Immune-Related Adverse Events and Associated Biomarkers in Patients Receiving Cancer Immunotherapy

NCT06089967

COMPLETED

Cognitive Disparities in Parkinson's Disease

NCT07262658

COMPLETED

EVeRLAST 2-Year Follow-Up

NCT05542836

COMPLETED NA

T2D Pilot Study for Patients With Uncontrolled Type 2 Diabetes

NCT06988540

COMPLETED NA

Caremap: A Digital Personal Health Record for Complex Care Coordination

NCT05056493

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What is open in the Duke University pipeline

187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).

Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).

Top condition: Obesity (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Duke University: open-pipeline peers nationwide

Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Duke UniversityUniversity of California, San FranciscoStanford UniversityVA Office of Research and DevelopmentPfizerCarnegie Mellon UniversityCAMC Health SystemUConn HealthHartford Hospital
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,725 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Duke University page

1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.

  • 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.