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NCT05764564 · ClinicalTrials.gov registry record · Phase 1
External Body Pressure in Heart Failure With Preserved Ejection Fraction
A Phase 1 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 1
- Development phase
- 27
- Enrollment target
NCT05764564: Completed Phase 1 study, sponsored by Duke University.
NCT05764564 is a Phase 1 study that has completed, run by Duke University. The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05764564, a Phase 1 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
The primary objective of the study is to test the impact of positive and negative body pressure on exercise capacity, symptoms, blood volume distribution and central cardiac hemodynamics in patients with heart failure and preserved ejection fraction. Aim 1 will study healthy volunteers and heart failure patients non invasively while Aim 2 will study heart failure patients invasively (intracardiac pressures).
Primary Outcome
Change in cardiac output from rest to 0 Watts exercise
Interventions
- DIAGNOSTIC_TEST Positive or negative pressure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2023-04-21 |
| Est. Completion | 2025-05-31 |
| Phase | Phase 1 |
What the finished NCT05764564 record still lists
NCT05764564 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 1 intervention - of which Positive or negative pressure is the first listed.
NCT05764564 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05764564 about?
NCT05764564 is a clinical study titled "External Body Pressure in Heart Failure With Preserved Ejection Fraction". The primary objective of the study is to test the impact of positive and negative body pressure on exercise capacity, symptoms, blood volume distribution and central cardiac hemodynamics in patients with heart failure and preserved ejection fraction. Aim 1 will study healthy volunteers and heart fai...
What is the current status of trial NCT05764564?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2023-04-21. Estimated completion is 2025-05-31.
What interventions are being tested in trial NCT05764564?
The interventions under investigation include: Positive or negative pressure (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05764564?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05764564's enrollment target sits among peer trials
27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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