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NCT05235321 · ClinicalTrials.gov registry record · NA
Automated Applanation Tonometry
A NA study, sponsored by Duke University.
- Terminated
- Registry status
- NA
- Development phase
- 111
- Enrollment target
NCT05235321: Clinical Trial NA study, sponsored by Duke University.
NCT05235321 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 111 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05235321, a NA study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- NA
- Development phase
- 111 participants
- Enrollment target
Study Summary
Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability. The purpose of this study is to develop an automated and objective method for performing applanation tonometry using standard ophthalmic equipment as well as using 2 portable prototypes.
Primary Outcome
this is the standard method for IOP measurement in clinical practice. The eye is given topical fluorescein/anesthetic, the GAT prism contacts the eye while the observer looks through the slit lamp machine ocular using blue light illumination to visual the applanation mires. The GAT dial is adjusted until mire alignment is achieved and the IOP measurement is read off the GAT dial.
Interventions
- DEVICE Standard GAT
- DEVICE Fixed force GAT
- DEVICE Upright applanating prototype
- DEVICE Supine Applanating Prototype
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 111 participants |
| Start Date | 2022-11-21 |
| Est. Completion | 2024-05-31 |
| Phase | NA |
Why NCT05235321 stopped before completion
NCT05235321 is an interventional study that assigns participants to a tested intervention. The registered 111 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 4 interventions - of which Standard GAT is the first listed.
NCT05235321 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05235321 about?
NCT05235321 is a clinical study titled "Automated Applanation Tonometry". Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability. The purpose of this study is to develop an automated and objective method for performing ...
What is the current status of trial NCT05235321?
This trial is currently terminated. It is a NA study. The enrollment target is 111 participants. The study started on 2022-11-21. Estimated completion is 2024-05-31.
What interventions are being tested in trial NCT05235321?
The interventions under investigation include: Standard GAT (DEVICE), Fixed force GAT (DEVICE), Upright applanating prototype (DEVICE), Supine Applanating Prototype (DEVICE).
Who is sponsoring clinical trial NCT05235321?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05235321's enrollment target sits among peer trials
111 816th of 2000 higher than 1,185 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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