Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 9 of 35
Senior PharmAssist: Co-Design and Evaluation of a Toolkit to Promote Scalable Implementation
NCT05278650
Inspiratory Muscle Rehabilitation in Children With Obesity
NCT05412134
Customized Approaches for Evaluating and Reducing Chemical Exposures From Home Building Materials
NCT05416281
Quantitative MRI of Glenohumeral Cartilage & Labrum in Shoulder Instability
NCT05431114
CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients
NCT04906213
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
NCT05465382
High Dose Inspiratory Muscle Training in LOPD
NCT05431127
DeStress for Health: Partnering With Granville and Vance Counties to Reduce Stress and Cancer Risk (Part 2)
NCT05469334
Low Nicotine Cigarettes, Smoking, and Chronic Pain
NCT05032755
Multimodal Management of Neck and Back Pain in the Emergency Department (Multi-ED)
NCT05221125
DBT for Metastatic Lung Cancer
NCT04973436
Durham Healthy Breathing in Healthy Homes Project
NCT04119271
Immune Correlates of Cardiac Structure and Function
NCT05328713
Voxelotor for Improving Oxygen Saturation in Adults
NCT05289570
Expanding Technology-Enabled Nurse Delivered Chronic Disease Care
NCT05120544
Diaphragm Function and Diver Endurance
NCT04679402
Diet and Hypertension Management in African Americans With Chronic Kidney Disease
NCT04084574
Pediatric Pain Optimization After Tonsillectomy
NCT05244226
A Pilot Study of a Micro-Organosphere Drug Screen Platform to Lead Care in Advanced Breast Cancer
NCT04655573
Safety of Pediatric COVID-19 Vaccination
NCT05157191
Step, Walk, Bike: Comparisons of Fitness Assessments
NCT04830306
MPS II Immunophenotyping
NCT04976231
Surveillance Pelvic Examination Anxiety: Brief Coping Skills Intervention
NCT05285306
Palliative Care Planner (PCplanner)
NCT05095363
Deprescribing for Older Dialysis Patients
NCT03631290
Network-guided TMS in Early Alzheimer's Disease
NCT04549155
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)
NCT04664101
Effect of Blueberry Supplementation on Alzheimer's Biomarkers
NCT05172128
Data-driven Approaches to Healthcare Provider Resilience & Burnout During COVID-19
NCT04922632
Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP
NCT05108935
Chompions! A Treatment Study for Childhood Avoidant/Restrictive Food Intake Disorder (ARFID)
NCT05105308
Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
NCT05125952
Patient Initiated Note About Goals
NCT05637489
Smokeless Tobacco Cessation Intervention for Firefighters
NCT05111041
Sepsis Characterization in Kilimanjaro
NCT05139459
Tailored to You (TTY) Pilot Study
NCT05141175
Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy
NCT05070351
Machine Learning to Predict Acute Care During Cancer Therapy
NCT05122247
Utilizing Qualitative and Quantitative Methods to Understand a New Model of Type 1 and 2 Systemic Lupus Erythematosus (SLE)
NCT05426902
Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy
NCT04567251
Movement-Oriented Behavioral Activation (MOBA)
NCT04892147
Comparing Effectiveness of CSE Versus DPE for Labor Analgesia
NCT05068661
You and Me COVID Free
NCT05212883
Particle Size Project
NCT05091801
ARFI Imaging for Targeted Prostate Biopsy
NCT04607135
Sleep Device Testing to Promote Sleep in Infants
NCT05078112
mHealth Behavioral Cancer Pain Intervention for Medically Underserved Patients
NCT04175639
Acceptability of Active Monitoring (AM) as a Treatment Option for Ductal Carcinoma in Situ (DCIS)
NCT03775213
Optimizing Parameters of Low-Intensity Focused Ultrasound for Cortical Modulation in Stroke Patients
NCT05016531
The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation
NCT04937413
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.