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NCT06181669 · ClinicalTrials.gov registry record
Pneumonia Direct Pilot
A clinical trial of Ventilator Associated Pneumonia and Pneumonia, Bacterial, sponsored by Duke University.
- Completed
- Registry status
- 173
- Enrollment target
- 4
- Study locations
NCT06181669: Completed study of Ventilator Associated Pneumonia and Pneumonia, Bacterial, sponsored by Duke University.
NCT06181669 is a study of Ventilator Associated Pneumonia and Pneumonia, Bacterial that has completed, run by Duke University. The registered enrollment target is 173 participants, above the 92-participant average among 7 other Ventilator Associated Pneumonia trials with a reported enrollment target (88% higher). The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06181669, a study of Ventilator Associated Pneumonia and Pneumonia, Bacterial, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- 173 participants
- Enrollment target
- 4
- Study locations
Study Summary
The Pneumonia Direct Pilot study is designed to assess whether combining molecular diagnostics for bacteria and AMR markers with host-response profiling improves agreement and predictive value for the diagnosis of VAP versus an adjudicated clinical reference standard. The feasibility design is intended to inform future interventional studies that will investigate the clinical impact of combined pathogen- and host-directed testing approaches.
Primary Outcome
This study will compare the results (positive, negative, or no result) of each index test.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Pathogen and Host Directed testing
Study Locations (4)
Michigan
- Henry Ford Hospital - Detroit
- Corewell (William Beaumont) - Royal Oak
Missouri
- Washington University School of Medicine in St. Louis - St Louis
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 173 participants |
| Start Date | 2024-04-12 |
| Est. Completion | 2025-07-03 |
What the finished NCT06181669 record still lists
NCT06181669 is an observational study that tracks outcomes without assigning an intervention. The registered 173 participants enrollment target is mid-sized for trials with a published cap, above the 92-participant average among 7 other Ventilator Associated Pneumonia trials with a reported enrollment target (88% higher).
The record links to 2 conditions, with Ventilator Associated Pneumonia appearing as the primary indexed condition, and to 1 intervention - of which Pathogen and Host Directed testing is the first listed.
NCT06181669 reports a single indexed study location in Michigan, Missouri, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06181669 about?
NCT06181669 is a clinical study titled "Pneumonia Direct Pilot". The Pneumonia Direct Pilot study is designed to assess whether combining molecular diagnostics for bacteria and AMR markers with host-response profiling improves agreement and predictive value for the diagnosis of VAP versus an adjudicated clinical reference standard. The feasibility design is inten...
What is the current status of trial NCT06181669?
This trial is currently completed. The enrollment target is 173 participants. The study started on 2024-04-12. Estimated completion is 2025-07-03.
What conditions does trial NCT06181669 study?
This clinical trial studies the following conditions: Ventilator Associated Pneumonia, Pneumonia, Bacterial.
What interventions are being tested in trial NCT06181669?
The interventions under investigation include: Pathogen and Host Directed testing (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06181669?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06181669 being conducted?
This trial has 4 study locations across Michigan, Missouri, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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