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NCT06181669 · ClinicalTrials.gov registry record

Pneumonia Direct Pilot

A clinical trial of Ventilator Associated Pneumonia and Pneumonia, Bacterial, sponsored by Duke University.

Completed
Registry status
173
Enrollment target
4
Study locations

NCT06181669 is a study of Ventilator Associated Pneumonia and Pneumonia, Bacterial that has completed, run by Duke University. The registered enrollment target is 173 participants, above the 92-participant average among 7 other Ventilator Associated Pneumonia trials with a reported enrollment target (88% higher). The trial reports 4 study locations across 3 states.

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The verdict

NCT06181669, a study of Ventilator Associated Pneumonia and Pneumonia, Bacterial, has completed, sponsored by Duke University.

COMPLETED
Registry status
173 participants
Enrollment target
4
Study locations

Study Summary

The Pneumonia Direct Pilot study is designed to assess whether combining molecular diagnostics for bacteria and AMR markers with host-response profiling improves agreement and predictive value for the diagnosis of VAP versus an adjudicated clinical reference standard. The feasibility design is intended to inform future interventional studies that will investigate the clinical impact of combined pathogen- and host-directed testing approaches.

Interventions

  • DIAGNOSTIC_TEST Pathogen and Host Directed testing

Study Locations (4)

Michigan

  • Henry Ford Hospital - Detroit
  • Corewell (William Beaumont) - Royal Oak

Missouri

  • Washington University School of Medicine in St. Louis - St Louis

Pennsylvania

  • University of Pittsburgh Medical Center - Pittsburgh

Trial Details

FieldValue
Enrollment Target 173 participants
Start Date 2024-04-12
Est. Completion 2025-07-03

Sponsor

Duke University

1,725 total trials

What the Registry Record Tells You About NCT06181669

The ClinicalTrials.gov registry entry for NCT06181669 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 173 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 92-participant average among 7 other Ventilator Associated Pneumonia trials with a reported enrollment target (88% higher). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Ventilator Associated Pneumonia appearing as the primary indexed condition, and to 1 intervention - of which Pathogen and Host Directed testing is the first listed.

NCT06181669 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Michigan, Missouri, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06181669 about?

NCT06181669 is a clinical study titled "Pneumonia Direct Pilot". The Pneumonia Direct Pilot study is designed to assess whether combining molecular diagnostics for bacteria and AMR markers with host-response profiling improves agreement and predictive value for the diagnosis of VAP versus an adjudicated clinical reference standard. The feasibility design is inten...

What is the current status of trial NCT06181669?

This trial is currently completed. The enrollment target is 173 participants. The study started on 2024-04-12. Estimated completion is 2025-07-03.

What conditions does trial NCT06181669 study?

This clinical trial studies the following conditions: Ventilator Associated Pneumonia, Pneumonia, Bacterial.

What interventions are being tested in trial NCT06181669?

The interventions under investigation include: Pathogen and Host Directed testing (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT06181669?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06181669 being conducted?

This trial has 4 study locations across Michigan, Missouri, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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