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NCT05940012 · ClinicalTrials.gov registry record · NA
Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 122
- Enrollment target
NCT05940012: Completed NA study, sponsored by Duke University.
NCT05940012 is a NA study that has completed, run by Duke University. The registered enrollment target is 122 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05940012, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 122 participants
- Enrollment target
Study Summary
It is expected that different physical therapy treatments influence outcomes in many different ways. Each treatment is assumed to have a "specific" treatment mechanism, which explains how that specific treatment works. Different treatments also have "shared" mechanisms, which are similar across many different types of interventions (e.g., exercise, cognitive treatments or manual therapy). In this study, the study team will investigate the several types of specific treatment mechanisms of a manual therapy-based approach and an exercise-based approach and the study team will compare these to see if they are different. The patient population will include individuals with chronic neck pain, which is a condition that leads to notable disability and pain. The study team will also evaluate several shared treatment mechanisms to see if these are similar across the two treatments (e.g., manual therapy versus exercise). The study team expects to find that there are some specific treatment mechanisms with each approach (manual therapy versus exercise) but also several "shared" mechanisms that are similar across the two seemingly different approaches. These will likely influence the outcomes and may help explain why clinicians see similar outcomes across both treatment groups for chronic neck pain. This study is important because no one has investigated whether the outcomes that occur with chronic neck pain are mostly influenced by specific or shared treatment mechanisms. Interestingly, in the psychological literature, shared treatment mechanisms demonstrate the strongest influence (more than specific treatment mechanisms).
Interventions
- OTHER Manual Therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 122 participants |
| Start Date | 2024-01-01 |
| Est. Completion | 2025-10-22 |
| Phase | NA |
What the finished NCT05940012 record still lists
NCT05940012 is an interventional study that assigns participants to a tested intervention. The registered 122 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which Manual Therapy is the first listed.
NCT05940012 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05940012 about?
NCT05940012 is a clinical study titled "Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain". It is expected that different physical therapy treatments influence outcomes in many different ways. Each treatment is assumed to have a "specific" treatment mechanism, which explains how that specific treatment works. Different treatments also have "shared" mechanisms, which are similar across many...
What is the current status of trial NCT05940012?
This trial is currently completed. It is a NA study. The enrollment target is 122 participants. The study started on 2024-01-01. Estimated completion is 2025-10-22.
What interventions are being tested in trial NCT05940012?
The interventions under investigation include: Manual Therapy (OTHER).
Who is sponsoring clinical trial NCT05940012?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05940012's enrollment target sits among peer trials
122 762nd of 2000 higher than 1,239 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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