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NCT07275359 · ClinicalTrials.gov registry record · Phase 1
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
A Phase 1 study, sponsored by Duke University.
- Not yet
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
NCT07275359: Clinical Trial Phase 1 study, sponsored by Duke University.
NCT07275359 is a Phase 1 study that has not yet begun recruiting, run by Duke University. The registered enrollment target is 45 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07275359, a Phase 1 study, has not yet begun recruiting, sponsored by Duke University.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate the safety and tolerability of Metformin and how it changes blood markers associated with aging in persons who have chronic obstructive pulmonary disease (COPD) who do not have diabetes.
Primary Outcome
Enroll and retain ≥ 30 (66%) participants through 6 months study period
Interventions
- DRUG Metformin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2026-09-01 |
| Est. Completion | 2029-10-02 |
| Phase | Phase 1 |
What is known before NCT07275359 opens enrollment
NCT07275359 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 1 intervention - of which Metformin is the first listed.
NCT07275359 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07275359 about?
NCT07275359 is a clinical study titled "Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations". The purpose of this study is to investigate the safety and tolerability of Metformin and how it changes blood markers associated with aging in persons who have chronic obstructive pulmonary disease (COPD) who do not have diabetes.
What is the current status of trial NCT07275359?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2026-09-01. Estimated completion is 2029-10-02.
What interventions are being tested in trial NCT07275359?
The interventions under investigation include: Metformin (DRUG).
Who is sponsoring clinical trial NCT07275359?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07275359's enrollment target sits among peer trials
45 1066th of 2000 higher than 915 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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