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NCT05905419 · ClinicalTrials.gov registry record · NA
Neuroimaging of Opioid Phase (OPAL)
A NA study of Chronic Pain and Opioid Use, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 140
- Enrollment target
- 1
- Study location
NCT05905419: Recruiting NA study of Chronic Pain and Opioid Use, sponsored by Duke University.
NCT05905419 is a NA study of Chronic Pain and Opioid Use that is actively recruiting participants, run by Duke University. The registered enrollment target is 140 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05905419, a NA study of Chronic Pain and Opioid Use, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.
Primary Outcome
Compare brain fMRI-based response to reward stimuli during a monetary incentive delay (MID) task and functional connectivity of brain reward circuitry during resting state.
Conditions Studied
Interventions
- OTHER Opioid Phase
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2023-06-01 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT05905419 shows while recruiting
NCT05905419 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (82% lower).
The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 1 intervention - of which Opioid Phase is the first listed.
NCT05905419 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT05905419 about?
NCT05905419 is a clinical study titled "Neuroimaging of Opioid Phase (OPAL)". The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.
What is the current status of trial NCT05905419?
This trial is currently recruiting. It is a NA study. The enrollment target is 140 participants. The study started on 2023-06-01. Estimated completion is 2027-06-30.
What conditions does trial NCT05905419 study?
This clinical trial studies the following conditions: Chronic Pain, Opioid Use.
What interventions are being tested in trial NCT05905419?
The interventions under investigation include: Opioid Phase (OTHER).
Who is sponsoring clinical trial NCT05905419?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05905419 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05905419's enrollment target sits among peer trials
140 110th of 301 higher than 192 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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