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NCT01899586 · ClinicalTrials.gov registry record · NA
Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 108
- Enrollment target
NCT01899586: Completed NA study, sponsored by Duke University.
NCT01899586 is a NA study that has completed, run by Duke University. The registered enrollment target is 108 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01899586, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 108 participants
- Enrollment target
Study Summary
The aim of this study is to devise a sufficiently high intensity training program that provided an optimal stimulus to remove the peripheral factors known to reduce functional capacity, and can be cardiovascular and orthopedically well tolerated by the elderly. Findings from study laboratories have suggested that a regional specific training stimulus (RSTS) results in rapid improvements in both vascular and muscular function. RSTS is a novel combination of resistance training and aerobic training applied simultaneously, and in a serial manner, to specific regions of the body. It involves high-intensity and frequency muscle contractions, generating a targeted exercise stimulus, without producing excessive cardiovascular or orthopedic stress. The hypothesis is that initiating training with RSTS at multiple, strategically selected peripheral sites, in a serial manner will elicit local vascular and muscular changes, thereby preparing individuals at elevated risk of losing independence, to respond and progress more favorably to whole-body exercise.
Primary Outcome
Exercise capacity was assessed using a maximal cardiopulmonary exercise (CPX) test with expired gas analysis, for determination of peak oxygen consumption and peak walking time.
Interventions
- OTHER Regional Specific Training Stimulus (RSTS)
- OTHER Aerobic Exercise Regimen (AE)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2009-09 |
| Est. Completion | 2011-11 |
| Phase | NA |
What the finished NCT01899586 record still lists
NCT01899586 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Regional Specific Training Stimulus (RSTS) is the first listed.
NCT01899586 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01899586 about?
NCT01899586 is a clinical study titled "Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly". The aim of this study is to devise a sufficiently high intensity training program that provided an optimal stimulus to remove the peripheral factors known to reduce functional capacity, and can be cardiovascular and orthopedically well tolerated by the elderly. Findings from study laboratories have ...
What is the current status of trial NCT01899586?
This trial is currently completed. It is a NA study. The enrollment target is 108 participants. The study started on 2009-09. Estimated completion is 2011-11.
What interventions are being tested in trial NCT01899586?
The interventions under investigation include: Regional Specific Training Stimulus (RSTS) (OTHER), Aerobic Exercise Regimen (AE) (OTHER).
Who is sponsoring clinical trial NCT01899586?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01899586's enrollment target sits among peer trials
108 825th of 2000 higher than 1,171 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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