Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 25 of 35

COMPLETED Phase 2

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

NCT01800968

COMPLETED

Comparative Study of Polymetric Clips (Hem-o-Lok) Versus Historical Endoscopic Staplers for Laparoscopic Appendectomy

NCT01830387

COMPLETED NA

Southeastern Diabetes Initiative Clinical Intervention

NCT01965639

COMPLETED

Translational Research Evaluating Neurocognitive Memory Processes

NCT01834677

COMPLETED

Study on Visual Function Impairments in Dry Age-related Macular Degeneration

NCT01822873

COMPLETED NA

Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery

NCT01812044

COMPLETED

Pelvic Ring Injury

NCT01821339

COMPLETED Phase 2

Evaluation of Circulating T Cells and Tumor Infiltrating Lymphocytes (TILs) During / After Pre-Surgery Chemotherapy in Non-Small Cell Lung Cancer (NSCLC)

NCT01820754

COMPLETED NA

Drug-Related Problems and Healthcare Utilization Post-Hospital Discharge

NCT01806038

COMPLETED NA

PLATFORM to Maximize Patient Knowledge of Health Goals After Acute Myocardial Infarction

NCT01807208

COMPLETED Phase 4

Safety Study of Aztreonam Lysine for Inhalation (AZLI) in the Treatment of Early Bronchiolitis Obliterans Syndrome (BOS)

NCT01469364

COMPLETED Phase 2

Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers

NCT01806779

TERMINATED Early Phase 1

The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia

NCT01905696

TERMINATED Phase 4

Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery

NCT01765270

TERMINATED Phase 2

Effects of Sildenafil on Choroidal Thickness in AMD

NCT01830790

COMPLETED NA

Carolina Alcohol and Drug Resources

NCT01791179

COMPLETED Phase 2

Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD

NCT01785524

COMPLETED NA

Pilot Testing a Patient and Provider Intervention for Managing Osteoarthritis in Hispanic Adults.

NCT01782417

COMPLETED

Microvascular and Fibrosis Imaging Study

NCT01758250

COMPLETED NA

Ultrasound in Muscle Biopsy

NCT01790178

COMPLETED

Neuromuscular Ultrasound in ALS

NCT01785550

COMPLETED NA

Total Knee Arthroplasty: Functional and Clinical Outcomes

NCT01811563

COMPLETED NA

Contingency Management for Smoking Cessation in Homeless Smokers

NCT01789710

COMPLETED

Characterizing and Comparing the Profile of Microorganisms From Specific Body Sites and Environmental Surfaces in Newly Disinfected Patient Rooms

NCT01803100

COMPLETED Phase 2

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

NCT01738646

COMPLETED Phase 4

Immediate vs. Delayed Postpartum Etonogestrel Implant

NCT01767285

COMPLETED NA

Optical Imaging and User Perception Study of Vaginal Gel

NCT01716000

COMPLETED NA

High Yield Intraoperative, Autologous Platelet Apheresis

NCT01819246

COMPLETED Phase 2

Bevacizumab Beyond Progression (BBP)

NCT01740258

COMPLETED

Serial Collection of Primary Progressive Multiple Sclerosis Participants in the MURDOCK Study

NCT01776060

COMPLETED NA

Hypercapnia: Cognitive Effects and Monitoring

NCT01782625

COMPLETED NA

Improving Decision Making for Patients With Prolonged Mechanical Ventilation

NCT01751061

TERMINATED Phase 2

Velcade + Cyclophosphamide in Newly Diagnosed Multiple Myeloma

NCT01729338

COMPLETED Phase 3

Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With Vilazodone

NCT02015546

COMPLETED

Pharmacogenetic Testing in Primary Care

NCT01600846

COMPLETED

Physiologic Mechanisms in Pediatric Traumatic Brain Injury (TBI)

NCT01763892

COMPLETED Phase 4

Dexamethasone for Post-cesarean Delivery Pain

NCT01812057

COMPLETED NA

Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)

NCT01840111

TERMINATED NA

Guiding Evidence Based Therapy Using Biomarker Intensified Treatment

NCT01685840

TERMINATED NA

Incisional Negative Pressure Wound Therapy

NCT01759381

COMPLETED Phase 4

Ranolazine for the Treatment of Chest Pain in HCM Patients

NCT01721967

COMPLETED NA

Exploring Massage Benefits for Arthritis of the Knee for VA Healthcare Users

NCT01714869

COMPLETED

Symptom Clusters in Children With Leukemia

NCT01708421

COMPLETED NA

Exploring Beliefs and Behaviors About Weight Loss in Couples

NCT01777711

COMPLETED NA

Cognitive Rehabilitation in Sickle Cell Disease

NCT01793740

COMPLETED NA

iCare vs Tonopen vs Goldmann Applanation Post-vitrectomy Surgery

NCT01786954

COMPLETED

Transplantation and the Use of Raltegravir in HIV-Infected Patients

NCT01793467

COMPLETED Phase 4

Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression

NCT01670019

COMPLETED Phase 3

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

NCT01644331

COMPLETED NA

Integrative Coping Group for Children

NCT01813669

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.