Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 25 of 35
Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)
NCT01800968
Comparative Study of Polymetric Clips (Hem-o-Lok) Versus Historical Endoscopic Staplers for Laparoscopic Appendectomy
NCT01830387
Southeastern Diabetes Initiative Clinical Intervention
NCT01965639
Translational Research Evaluating Neurocognitive Memory Processes
NCT01834677
Study on Visual Function Impairments in Dry Age-related Macular Degeneration
NCT01822873
Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery
NCT01812044
Pelvic Ring Injury
NCT01821339
Evaluation of Circulating T Cells and Tumor Infiltrating Lymphocytes (TILs) During / After Pre-Surgery Chemotherapy in Non-Small Cell Lung Cancer (NSCLC)
NCT01820754
Drug-Related Problems and Healthcare Utilization Post-Hospital Discharge
NCT01806038
PLATFORM to Maximize Patient Knowledge of Health Goals After Acute Myocardial Infarction
NCT01807208
Safety Study of Aztreonam Lysine for Inhalation (AZLI) in the Treatment of Early Bronchiolitis Obliterans Syndrome (BOS)
NCT01469364
Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers
NCT01806779
The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia
NCT01905696
Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery
NCT01765270
Effects of Sildenafil on Choroidal Thickness in AMD
NCT01830790
Carolina Alcohol and Drug Resources
NCT01791179
Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD
NCT01785524
Pilot Testing a Patient and Provider Intervention for Managing Osteoarthritis in Hispanic Adults.
NCT01782417
Microvascular and Fibrosis Imaging Study
NCT01758250
Ultrasound in Muscle Biopsy
NCT01790178
Neuromuscular Ultrasound in ALS
NCT01785550
Total Knee Arthroplasty: Functional and Clinical Outcomes
NCT01811563
Contingency Management for Smoking Cessation in Homeless Smokers
NCT01789710
Characterizing and Comparing the Profile of Microorganisms From Specific Body Sites and Environmental Surfaces in Newly Disinfected Patient Rooms
NCT01803100
Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients
NCT01738646
Immediate vs. Delayed Postpartum Etonogestrel Implant
NCT01767285
Optical Imaging and User Perception Study of Vaginal Gel
NCT01716000
High Yield Intraoperative, Autologous Platelet Apheresis
NCT01819246
Bevacizumab Beyond Progression (BBP)
NCT01740258
Serial Collection of Primary Progressive Multiple Sclerosis Participants in the MURDOCK Study
NCT01776060
Hypercapnia: Cognitive Effects and Monitoring
NCT01782625
Improving Decision Making for Patients With Prolonged Mechanical Ventilation
NCT01751061
Velcade + Cyclophosphamide in Newly Diagnosed Multiple Myeloma
NCT01729338
Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With Vilazodone
NCT02015546
Pharmacogenetic Testing in Primary Care
NCT01600846
Physiologic Mechanisms in Pediatric Traumatic Brain Injury (TBI)
NCT01763892
Dexamethasone for Post-cesarean Delivery Pain
NCT01812057
Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)
NCT01840111
Guiding Evidence Based Therapy Using Biomarker Intensified Treatment
NCT01685840
Incisional Negative Pressure Wound Therapy
NCT01759381
Ranolazine for the Treatment of Chest Pain in HCM Patients
NCT01721967
Exploring Massage Benefits for Arthritis of the Knee for VA Healthcare Users
NCT01714869
Symptom Clusters in Children With Leukemia
NCT01708421
Exploring Beliefs and Behaviors About Weight Loss in Couples
NCT01777711
Cognitive Rehabilitation in Sickle Cell Disease
NCT01793740
iCare vs Tonopen vs Goldmann Applanation Post-vitrectomy Surgery
NCT01786954
Transplantation and the Use of Raltegravir in HIV-Infected Patients
NCT01793467
Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression
NCT01670019
Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure
NCT01644331
Integrative Coping Group for Children
NCT01813669
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.