Duke University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).

1,725 total trials 187 currently recruiting 1244 completed early-phase tilt top decile by trial count

Duke University: 1,725 sponsored US clinical trials, 187 recruiting.

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Top-decile sponsor footprint

Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,725 total, page 24 of 35

COMPLETED

Self-Reported Exercise Behavior and Short-Term Patient Outcomes in Women Undergoing Radiation Treatment for Operable Breast Cancer

NCT02050620

COMPLETED Phase 4

Thoracoabdominal Arortic CTA Study

NCT02291718

TERMINATED

Ammonia Levels and Cognitive Impairment

NCT02059356

COMPLETED NA

Negative Pressure Wound Therapy to Reduce Surgical Site Infection

NCT01905397

COMPLETED NA

Carbohydrate Restriction and Prostate Cancer Growth

NCT01763944

COMPLETED NA

Development of Novel Therapies for NIDDM

NCT01905722

COMPLETED Phase 4

Effects of Ranolazine and Exercise on Daily Physical Activity Trial

NCT01948310

COMPLETED NA

Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD

NCT01990079

COMPLETED NA

Pancreatic Resection, Malnutrition and Readmission

NCT01947166

COMPLETED Phase 2

Valproic Acid for the Prevention of Post-Amputation Pain

NCT01928849

TERMINATED NA

Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy

NCT02164929

COMPLETED Early Phase 1

GM03 - Platelet RNA Signatures of Aspirin

NCT05278637

COMPLETED

Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research

NCT02146274

COMPLETED NA

Medication Therapy Management With Pharmacogenetic Testing

NCT01970774

COMPLETED Phase 1

A Pilot Study of Ipilumimab and Radiation in Poor Prognosis Melanoma

NCT01996202

COMPLETED Phase 1

Immunotherapy With CEA(6D) VRP Vaccine (AVX701) in Patients With Stage III Colorectal Cancer

NCT01890213

COMPLETED Phase 4

Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care

NCT01993836

COMPLETED NA

mPCST for BMT Patients

NCT01984671

COMPLETED NA

Improving Adherence to Recommended Surveillance in Breast Cancer Survivors

NCT02189278

COMPLETED NA

Advancing the Standard of Care for Pin Site Care

NCT01965665

COMPLETED

Lymphedema in Endometrial Cancer

NCT01914276

COMPLETED Phase 4

Clinical Immunization Safety Assessment (CISA) Project: Pilot Study to Assess the Effect of Prophylactic Antipyretics on Immune Responses and Fever After IIV

NCT01946594

COMPLETED Phase 2

Abiraterone Race in Metastatic Castrate-resistant Prostate Cancer

NCT01940276

COMPLETED

PVI for Prediction of Spinal Induced Hypotension

NCT01967914

COMPLETED NA

Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers

NCT01983254

TERMINATED Phase 3

Epidural Analgesia Versus IV Analgesia in Lumbar Spine Fusions

NCT01986946

COMPLETED

Socio-Economic Survey in Uganda

NCT01971697

COMPLETED

Novel Retinal Imaging Biomarkers in Early Alzheimer's Disease

NCT01937221

COMPLETED

Feasibility of Blood Oxygenation Level-Dependent Contrast (BOLD) Breast MRI Induced by Breath- Holding

NCT01898533

COMPLETED NA

The Effect of Scheduled Ripcord Removal on the Outcomes of Baerveldt 350 Implants

NCT01915706

TERMINATED NA

Automated MEdical Record Driven Implantable CArdioverter-defibrillator Heart Failure Trial (AMERICA-HF)

NCT01807130

COMPLETED NA

Screening, Brief Intervention, and Referral to Treatment in Primary Care

NCT01966432

COMPLETED NA

Third Ventriculostomy Versus Shunt for Children With Hydrocephalus

NCT01801267

COMPLETED NA

The Early Truancy Prevention Project

NCT01894464

COMPLETED

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

NCT01904175

COMPLETED Phase 1

Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease

NCT01895998

COMPLETED

Triadic Expectations: Decision Making in the Context of Cancer Treatment

NCT01898481

COMPLETED NA

The Effect of Prophylactic FFP Administration on ECMO Circuit Longevity

NCT01903863

COMPLETED NA

Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease

NCT01884545

COMPLETED

Therapeutic Plasma Exchange in MG

NCT01927692

COMPLETED NA

Genetically Guided Statin Therapy

NCT01894230

COMPLETED NA

Comparison of Transbronchial, Cryoprobe and VATS Biopsy For the Diagnosis of Interstitial Lung Disease (ILD)

NCT01972685

COMPLETED NA

New Media Obesity Treatment in Community Health Centers

NCT01827800

COMPLETED NA

Effect of CPAP on Postoperative Delirium

NCT01816685

COMPLETED NA

Freezing of Gait in Parkinson's Disease

NCT01887054

COMPLETED Phase 1

Safety and Efficacy of Albuterol in Individuals With Late-onset Pompe Disease

NCT01885936

TERMINATED NA

ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients

NCT01867047

COMPLETED

Longitudinal Assessment of Cardiovascular and Renal Health in Patients With Hepatitis-C (CARE-Hep C)

NCT01846494

COMPLETED

Bone Metabolism After Bariatric Surgery

NCT01824797

COMPLETED

Comparative Effectiveness of Rehabilitation Services for Survivors of Acute Ischemic Stroke

NCT02284165

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What is open in the Duke University pipeline

187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).

Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).

Top condition: Obesity (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Duke University: open-pipeline peers nationwide

Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Duke UniversityUniversity of California, San FranciscoStanford UniversityVA Office of Research and DevelopmentPfizerCarnegie Mellon UniversityCAMC Health SystemUConn HealthHartford Hospital
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,725 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Duke University page

1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.

  • 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.