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NCT01905696 · ClinicalTrials.gov registry record · Early Phase 1
The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia
A Early Phase 1 study, sponsored by Duke University.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 10
- Enrollment target
NCT01905696: Clinical Trial Early Phase 1 study, sponsored by Duke University.
NCT01905696 is a Early Phase 1 study that was terminated before completion, run by Duke University. The registered enrollment target is 10 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01905696, a Early Phase 1 study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
Nitric oxide is believed to contribute to regulation of blood flow by its selective binding to circulating hemoglobin (forming S-nitrosohemoglobin, SNO-Hb) and release in a PO2-dependent manner. This study is designed to test that hypothesis by measuring the effect of hypoxia and exercise on forearm blood flow before and after depletion of SNO-Hb using oral N-acetylcysteine.
Interventions
- DRUG Oral N-acetylcysteine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2013-03 |
| Est. Completion | 2013-08 |
| Phase | Early Phase 1 |
Why NCT01905696 stopped before completion
NCT01905696 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 1 intervention - of which Oral N-acetylcysteine is the first listed.
NCT01905696 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01905696 about?
NCT01905696 is a clinical study titled "The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia". Nitric oxide is believed to contribute to regulation of blood flow by its selective binding to circulating hemoglobin (forming S-nitrosohemoglobin, SNO-Hb) and release in a PO2-dependent manner. This study is designed to test that hypothesis by measuring the effect of hypoxia and exercise on forearm...
What is the current status of trial NCT01905696?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2013-03. Estimated completion is 2013-08.
What interventions are being tested in trial NCT01905696?
The interventions under investigation include: Oral N-acetylcysteine (DRUG).
Who is sponsoring clinical trial NCT01905696?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01905696's enrollment target sits among peer trials
10 1628th of 2000 higher than 256 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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