Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01812057 · ClinicalTrials.gov registry record · Phase 4

Dexamethasone for Post-cesarean Delivery Pain

A Phase 4 study, sponsored by Duke University.

Completed
Registry status
Phase 4
Development phase
53
Enrollment target

NCT01812057: Completed Phase 4 study, sponsored by Duke University.

NCT01812057 is a Phase 4 study that has completed, run by Duke University. The registered enrollment target is 53 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01812057, a Phase 4 study, has completed, sponsored by Duke University.

COMPLETED
Registry status
Phase 4
Development phase
53 participants
Enrollment target

Study Summary

The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative steroid (dexamethasone 8 milligrams) versus placebo at 24 hours after surgery. The hypothesis is that a single perioperative dose of dexamethasone 8 mg will significantly reduce postoperative opioid consumption at 24 h in women having cesarean delivery under spinal anesthesia.

Primary Outcome

The primary outcome will be the cumulative morphine consumption at 24 h in the two study groups. All postoperative opioids were converted to IV morphine equivalents using the following conversion factors: 100 micrograms IV = 10 mg IV morphine, 20 mg oxycodone po = 10 mg IV Morphine

Interventions

  • DRUG Placebo
  • DRUG Dexamethasone

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2012-12
Est. Completion 2016-09-21
Phase Phase 4
Duke University

1,725 total trials

What the finished NCT01812057 record still lists

NCT01812057 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01812057 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01812057 about?

NCT01812057 is a clinical study titled "Dexamethasone for Post-cesarean Delivery Pain". The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative steroid (dexamethasone 8 milligrams) versus placebo at 24 hours after surger...

What is the current status of trial NCT01812057?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 53 participants. The study started on 2012-12. Estimated completion is 2016-09-21.

What interventions are being tested in trial NCT01812057?

The interventions under investigation include: Placebo (DRUG), Dexamethasone (DRUG).

Who is sponsoring clinical trial NCT01812057?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01812057's enrollment target sits among peer trials

53 1229th of 2000 higher than 768 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04177004 · 53 participants · Phase 1

    Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

  • NCT04199741 · 53 participants · Phase 1

    PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

  • NCT04835129 · 53 participants · Phase 2

    Isatuximab, Pomalidomide, Elotuzumab and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma

  • NCT04913805 · 53 participants · Phase 2

    Matching Perfusion and Metabolic Activity in HFpEF

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01812057, the US trial registry maintained by the National Library of Medicine. NCT01812057 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.