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NCT01993836 · ClinicalTrials.gov registry record · Phase 4
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
A Phase 4 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 4
- Development phase
- 191
- Enrollment target
NCT01993836 is a Phase 4 study that has completed, run by Duke University. The registered enrollment target is 191 participants.
The verdict
NCT01993836, a Phase 4 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 191 participants
- Enrollment target
Study Summary
This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal cord (i.e. cerebrospinal fluid, or CSF), and/or changes in brain connectivity. The investigators will also examine whether different types of anesthesia have different effects on these CSF markers of Alzheimers disease, or different effects on thinking and memory after anesthesia and surgery, or differential effects on the correlation between cognitive changes and CSF marker changes.
Interventions
- DRUG Total intravenous anesthesia with propofol
- DRUG General anesthesia with isoflurane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 191 participants |
| Start Date | 2013-11 |
| Est. Completion | 2019-01-10 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01993836
The ClinicalTrials.gov registry entry for NCT01993836 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 191 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Total intravenous anesthesia with propofol is the first listed.
NCT01993836 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01993836 about?
NCT01993836 is a clinical study titled "Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care". This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal cord (i.e. cerebrospinal fluid, or CSF), and/or changes in brain connecti...
What is the current status of trial NCT01993836?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 191 participants. The study started on 2013-11. Estimated completion is 2019-01-10.
What interventions are being tested in trial NCT01993836?
The interventions under investigation include: Total intravenous anesthesia with propofol (DRUG), General anesthesia with isoflurane (DRUG).
Who is sponsoring clinical trial NCT01993836?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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