Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 13 of 35
Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder
NCT03987581
Using fMRI-guided TMS to Increase Central Executive Function in Older Adults (MCI_Sub)
NCT04176406
Improving Lung Transplant Outcomes With Coping Skills and Physical Activity
NCT04093869
Varenicline Light Smoking Pilot
NCT04089982
Targeting Infant Development With Early Screening
NCT04326179
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
NCT03844412
AML Expressive Writing
NCT04006496
HIP: Hip Imaging Protocol
NCT04126161
Computational Modeling of Cleft Lip Nasal Deformity and Assessment of Nasal Function and Treatment Outcomes
NCT04150783
Assessing Muscle Metabolic Phenotype by MSK Ultrasound
NCT04353648
Consequences of Marijuana Use in HIV-infected Youth
NCT03927053
QL Block With Exparel in Colectomy
NCT03827291
Newborn Nursery Reach Out and Read
NCT04147429
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
NCT03938324
Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA)
NCT03841357
Reducing Disparities in Medication Adherence in SLE
NCT03738826
Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome
NCT04053452
Effect of Octreotide on Saliva
NCT05340192
Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
NCT04049162
Anterior Corneal Striae in Hypotony
NCT04023123
Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section
NCT03695172
An Opioid Prescribing Nudge
NCT04069403
Nicotine Withdrawal and Reward Processing: Connecting Neurobiology to Real-world Behavior
NCT03840694
Safety of RIV4 Versus IIV4 in Pregnant Women
NCT03969641
Impact of Body Habitus (Arm Span and Abdominal Girth) on Activities of Daily Living (ADL)
NCT04037059
Transcranial Direct Current Stimulation for Post-stroke Motor Recovery
NCT03826030
Measuring the Impact of an Enhanced Strategy for Daily Disinfection in Acute Care Hospital Rooms
NCT05560321
Development of a Cabozantinib (Cabometyx) Symptom Management Application for Use in Patients With Renal Cancer
NCT03867045
Comparison of the Accuracy of Telehealth Examination Versus Clinical Examination in the Detection of Rotator Cuff Tears
NCT03906630
Optimizing a Mobile Mindfulness Intervention for ICU Survivors
NCT04038567
Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease
NCT03933397
Prospective Randomized Trial of Streamlined Genetic Education and Testing for Ovarian Cancer Patients
NCT04537702
Measurements From Stool to Support Dietary Change
NCT04037306
A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease
NCT03936660
In Person and mHealth Coping Skills Training for Symptom Management and Steps in Stem Cell Transplant Patients
NCT03859765
Expressive Writing for Cancer Survivors
NCT04171609
Durham Housing Authority (DHA) Community Health Advisor (CHA) Smoking Cessation Project
NCT04114526
DOSE Trial of Opioid Sparing Effect
NCT03938857
In Person and Mobile Health Coping Skills Training for Improving Symptom Management and Daily Steps in Hematopoietic Stem Cell Transplant Patients
NCT03960619
Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention
NCT03686813
NT-proBNP Levels and Obesity in Pregnancy
NCT04049136
Latina Adolescent Depression Treatment Study
NCT04164537
Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
NCT03781089
Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer
NCT03719495
Opioid Sparing Potential of Light-Induced Analgesia
NCT03890419
Effects of Connectivity-based rTMS and State-Dependency on Amygdala Activation
NCT03746405
Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion
NCT03976219
Measuring Effects of Prebiotics on Human Behavior and Cognition
NCT04055246
Cancer Treatment Decision-making in the HIV Population: an Observational Study of Physician-patient Interactions
NCT03721796
Utility of Postoperative Bracing
NCT03947541
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.