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COMPLETED Phase 2

Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

NCT03826030 · View on ClinicalTrials.gov ↗

Study Summary

This research study is to find out if brain stimulation at different dosage level combined with an efficacy-proven rehabilitation therapy can improve arm function. The stimulation technique is called transcranial direct current stimulation (tDCS). The treatment uses direct currents to stimulate specific parts of the brain affected by stroke. The adjunctive rehabilitation therapy is called "modified Constraint-Induced Movement Therapy" (mCIMT). During this therapy the subject will wear a mitt on the hand of the arm that was not affected by a stroke and force to use the weak arm. The study will test 3 different doses of brain stimulation in combination with mCIMT to find out the most promising one.

Interventions

  • DEVICE Sham
  • DEVICE Low dose tDCS
  • DEVICE High dose tDCS
  • BEHAVIORAL mCIMT

Study Locations (14)

Ohio

  • University of Cincinnati Medical Center — Cincinnati
  • Cleveland VA Medical Center — Cleveland

Pennsylvania

  • Moss Rehabilitation Research Institute — Elkins Park
  • University of Pittsburgh Medical Center Presbyterian Hospital — Pittsburgh

Alabama

  • University of Alabama at Birmingham Hospital — Birmingham

California

  • Keck Hospital of USC — Los Angeles

District of Columbia

  • MedStar National Rehabilitation Hospital — Washington D.C.

Georgia

  • Emory Rehabilitation Hospital — Atlanta

Kentucky

  • Cardinal Hill Rehabilitation Hospital — Lexington

Massachusetts

  • Baystate Medical Center — Springfield

Trial Details

FieldValue
Enrollment Target 129 participants
Start Date 2019-09-01
Est. Completion 2024-09-19
Phase Phase 2

Sponsor

Duke University

1,129 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03826030

The ClinicalTrials.gov registry entry for NCT03826030 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 129 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,129 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Stroke, Ischemic appearing as the primary indexed condition, and to 4 interventions — of which Sham is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03826030 reports 14 study locations spanning 12 distinct geographic areas — top geographies include Ohio, Pennsylvania, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03826030 about?

NCT03826030 is a clinical study titled "Transcranial Direct Current Stimulation for Post-stroke Motor Recovery". This research study is to find out if brain stimulation at different dosage level combined with an efficacy-proven rehabilitation therapy can improve arm function. The stimulation technique is called transcranial direct current stimulation (tDCS). The treatment uses direct currents to stimulate spec...

What is the current status of trial NCT03826030?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 129 participants. The study started on 2019-09-01. Estimated completion is 2024-09-19.

What conditions does trial NCT03826030 study?

This clinical trial studies the following conditions: Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03826030?

The interventions under investigation include: Sham (DEVICE), Low dose tDCS (DEVICE), High dose tDCS (DEVICE), mCIMT (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03826030?

This trial is sponsored by Duke University, which has 1,129 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03826030 being conducted?

This trial has 14 study locations across Alabama, California, District of Columbia, Georgia, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial