Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 12 of 35

COMPLETED NA

Individual Patient Exposure and Response in Pediatric Lupus

NCT04358302

COMPLETED NA

RESILIENCE: Personalizing Cardiovascular Health

NCT04551872

COMPLETED NA

Patient-Derived Organoids for Rectal Cancer

NCT04371198

COMPLETED

Skeletal Muscle Health in Children With Type 1 Diabetes

NCT04288063

COMPLETED NA

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

NCT04546061

COMPLETED Phase 2

Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

NCT04352777

COMPLETED NA

Exploring Two Treatments for Misophonia

NCT04198597

COMPLETED NA

MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics

NCT04226131

TERMINATED Phase 4

Persistent Postpartum Hypertension Pilot Trial

NCT04349124

COMPLETED Phase 4

Aspirin for Prevention of Venous Thromboembolism Among Ovarian Cancer Patients Receiving Neoadjuvant Chemotherapy

NCT04352439

COMPLETED

COA-APTIC Clinician Concept Elicitation Study

NCT04380246

COMPLETED Phase 4

Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia

NCT04158752

COMPLETED NA

Daxor - Blood Volume Analysis

NCT04111185

COMPLETED

Perioperative Tissue Penetration of Antimicrobials in Infants

NCT04299867

COMPLETED NA

Genetic Testing to Understand and Address Renal Disease Disparities Across the United States

NCT04191824

COMPLETED NA

Genetic Testing to Understand and Address Renal Disease Disparities Across the United States Pharmacogenetic Substudy

NCT06748040

TERMINATED Phase 2

Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib

NCT04099836

COMPLETED NA

Expedited Versus Restrictive: Limitations on Activity Following Surgical Treatment of Prolapse

NCT04329715

COMPLETED NA

Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19

NCT04399252

COMPLETED

MURDOCK Cabarrus County COVID-19 Prevalence and Immunity (C3PI) Study

NCT04424004

COMPLETED NA

Reducing Obesity and Cartilage Compression in Knees

NCT04730557

COMPLETED NA

Expressive Writing for COVID-19 Resilience for Parents

NCT04589117

COMPLETED NA

Expressive Writing for COVID-19 Resilience

NCT04589104

COMPLETED NA

Pattern - Reach Aim 2

NCT04216264

COMPLETED Phase 2

NeuroCognition After Carotid Recanalization

NCT04219774

COMPLETED

Longitudinal Energy Expenditure and Metabolic Effects in Patients With COVID-19 (LEEP-COVID)

NCT04350073

TERMINATED Phase 2

Pragmatic Factorial Trial of Hydroxychloroquine, Azithromycin, or Both for Treatment of Severe SARS-CoV-2 Infection

NCT04335552

COMPLETED

Healthcare Worker Exposure Response and Outcomes (HERO) Registry Study, COVID-19

NCT04342806

TERMINATED Phase 1

A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib

NCT04253223

COMPLETED

COVID-19 Pandemic Response Network

NCT04320862

COMPLETED NA

Self-System Therapy for Older Adults With Lung Cancer

NCT04057196

TERMINATED Phase 2

Immediate Prostatectomy vs. Cabozantinib Followed by Prostatectomy in Men With High-Risk Prostate Cancer

NCT03964337

COMPLETED NA

Virtual Reality for Improving Pain and Distress in Patients With Advanced Stage Colorectal Cancer

NCT04069702

TERMINATED NA

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

NCT04095039

COMPLETED

Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders

NCT04399694

COMPLETED NA

AdheRence to Inhaled Corticosteroids in Asthma

NCT03769519

COMPLETED

Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2

NCT04235309

COMPLETED NA

Sleep Quality and Mechanisms of Cardiovascular Risks in Adults With Hypertension

NCT04009447

COMPLETED NA

Emergency Department Acupuncture for Acute Musculoskeletal Pain Management

NCT04290741

COMPLETED NA

Arterial Versus Venous Activated Clotting Time (ACT) Measurements During Atrial Fibrillation Ablations

NCT04285840

COMPLETED Phase 2

Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)

NCT04575428

COMPLETED NA

Improving the Clinical Encounter to Enhance Delivery of an Individualized Prematurity Prevention Plan

NCT04149002

COMPLETED

CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean

NCT04271072

COMPLETED NA

Symptom Management for YA Cancer Survivors

NCT04035447

COMPLETED NA

Respiratory Muscle Training (RMT) in ALS

NCT04224961

COMPLETED NA

Selah Trial of Stress Interventions for Clergy: Mindfulness Based Stress Reduction, Daily Examen, and Stress Inoculation

NCT04625777

COMPLETED

Clinical Trials in Organ Transplantation Extension Study

NCT04126746

TERMINATED NA

Hypertension Management in Cancer Patients

NCT03919214

COMPLETED

BEST vCLI Registry

NCT04191746

COMPLETED

Quality Improvement Project for Advance Care Planning Tool in Hospital Medicine

NCT04296136

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.