Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 12 of 35
Individual Patient Exposure and Response in Pediatric Lupus
NCT04358302
RESILIENCE: Personalizing Cardiovascular Health
NCT04551872
Patient-Derived Organoids for Rectal Cancer
NCT04371198
Skeletal Muscle Health in Children With Type 1 Diabetes
NCT04288063
Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities
NCT04546061
Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer
NCT04352777
Exploring Two Treatments for Misophonia
NCT04198597
MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics
NCT04226131
Persistent Postpartum Hypertension Pilot Trial
NCT04349124
Aspirin for Prevention of Venous Thromboembolism Among Ovarian Cancer Patients Receiving Neoadjuvant Chemotherapy
NCT04352439
COA-APTIC Clinician Concept Elicitation Study
NCT04380246
Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia
NCT04158752
Daxor - Blood Volume Analysis
NCT04111185
Perioperative Tissue Penetration of Antimicrobials in Infants
NCT04299867
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States
NCT04191824
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States Pharmacogenetic Substudy
NCT06748040
Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib
NCT04099836
Expedited Versus Restrictive: Limitations on Activity Following Surgical Treatment of Prolapse
NCT04329715
Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19
NCT04399252
MURDOCK Cabarrus County COVID-19 Prevalence and Immunity (C3PI) Study
NCT04424004
Reducing Obesity and Cartilage Compression in Knees
NCT04730557
Expressive Writing for COVID-19 Resilience for Parents
NCT04589117
Expressive Writing for COVID-19 Resilience
NCT04589104
Pattern - Reach Aim 2
NCT04216264
NeuroCognition After Carotid Recanalization
NCT04219774
Longitudinal Energy Expenditure and Metabolic Effects in Patients With COVID-19 (LEEP-COVID)
NCT04350073
Pragmatic Factorial Trial of Hydroxychloroquine, Azithromycin, or Both for Treatment of Severe SARS-CoV-2 Infection
NCT04335552
Healthcare Worker Exposure Response and Outcomes (HERO) Registry Study, COVID-19
NCT04342806
A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib
NCT04253223
COVID-19 Pandemic Response Network
NCT04320862
Self-System Therapy for Older Adults With Lung Cancer
NCT04057196
Immediate Prostatectomy vs. Cabozantinib Followed by Prostatectomy in Men With High-Risk Prostate Cancer
NCT03964337
Virtual Reality for Improving Pain and Distress in Patients With Advanced Stage Colorectal Cancer
NCT04069702
HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis
NCT04095039
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders
NCT04399694
AdheRence to Inhaled Corticosteroids in Asthma
NCT03769519
Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2
NCT04235309
Sleep Quality and Mechanisms of Cardiovascular Risks in Adults With Hypertension
NCT04009447
Emergency Department Acupuncture for Acute Musculoskeletal Pain Management
NCT04290741
Arterial Versus Venous Activated Clotting Time (ACT) Measurements During Atrial Fibrillation Ablations
NCT04285840
Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)
NCT04575428
Improving the Clinical Encounter to Enhance Delivery of an Individualized Prematurity Prevention Plan
NCT04149002
CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean
NCT04271072
Symptom Management for YA Cancer Survivors
NCT04035447
Respiratory Muscle Training (RMT) in ALS
NCT04224961
Selah Trial of Stress Interventions for Clergy: Mindfulness Based Stress Reduction, Daily Examen, and Stress Inoculation
NCT04625777
Clinical Trials in Organ Transplantation Extension Study
NCT04126746
Hypertension Management in Cancer Patients
NCT03919214
BEST vCLI Registry
NCT04191746
Quality Improvement Project for Advance Care Planning Tool in Hospital Medicine
NCT04296136
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.