Columbia University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Columbia University sits in the top decile of US sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count).

958 total trials 171 currently recruiting 597 completed early-phase tilt top decile by trial count

Columbia University: 958 sponsored US clinical trials, 171 recruiting.

Columbia University sponsors 958 registered US clinical trials on ClinicalTrials.gov, 171 of them currently recruiting, and 597 completed. 88 of these trials are in Phase 3-4 (later-stage) and 191 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 9 trials.

Top-decile sponsor footprint

Columbia University ranks in the top decile of sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

597 of 736 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

958 total, page 13 of 20

COMPLETED

Macular Damage in Early Glaucoma and Progression

NCT02547740

COMPLETED Phase 4

Ticagrelor Therapy for RefrACTORy Migraine Study

NCT02518464

COMPLETED NA

Quantitative Imaging Biomarkers for Sarcoma

NCT02579980

TERMINATED Early Phase 1

MRI and PET to Assess Pembrolizumab Response

NCT02591654

COMPLETED Phase 4

2 Dose Neuraxial Morphine for Prevention of PDPH

NCT02473276

TERMINATED Phase 4

Acetaminophen and Post Circumcision Pain Control

NCT02498483

COMPLETED NA

Creating Opportunities Through Mentoring, Parental Involvement and Safe Spaces - Ethiopia

NCT02506543

COMPLETED NA

Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome

NCT02513784

COMPLETED Phase 4

EC PK in Women With Normal and Obese BMI

NCT02689804

COMPLETED Phase 1

Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart

NCT02462941

COMPLETED NA

Ultrasound vs Palpation for Infant Lumbar Puncture

NCT02373774

COMPLETED Phase 3

Intranasal Ketorolac Versus Intravenous Ketorolac for Treatment of Migraine Headaches in Children

NCT02358681

COMPLETED NA

Creating Opportunities Through Mentoring, Parenting and Safe Spaces - Democratic Republic of Congo

NCT02384642

TERMINATED NA

Transcranial Direct Current Stimulation for Post-Stroke Aphasia

NCT02461355

COMPLETED Phase 2

Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.

NCT02437669

COMPLETED NA

Effects of CPAP on Diet, Physical Activity, and Cardiovascular Risk

NCT01944020

COMPLETED

Microfinance Institutions as a Platform for Global Health

NCT02808117

COMPLETED

The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia

NCT05172687

COMPLETED Phase 4

PrEPared and Strong: Clinic-Based PrEP for Black MSM

NCT02167386

COMPLETED Phase 2

Crizotinib in High-Risk Uveal Melanoma Following Definitive Therapy

NCT02223819

COMPLETED NA

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

NCT02731326

COMPLETED Phase 4

Evaluation of Ureteral Patency in the Post-indigo Carmine Era

NCT02677623

COMPLETED NA

Microbiome, Exercise Tracking Study: Among Individuals at High Risk for Colorectal Cancer

NCT02780284

COMPLETED NA

Immediate or Delayed Provisionalization in Posterior Healed Sites

NCT02387970

TERMINATED Phase 3

Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?

NCT04080505

COMPLETED

Web-based Validation Pelvic Floor Questionnaires

NCT02724891

COMPLETED

Antigen Presentation and Lymphocyte Response in Parkinson's Disease

NCT02939534

TERMINATED NA

Early Behavioral Intervention for Preterm Infants

NCT02379130

TERMINATED Phase 1

Pharmacokinetics of Intranasal Ketorolac in Children

NCT02297906

COMPLETED Phase 2

Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And Universalis

NCT02299297

COMPLETED NA

Closed Suction Drainage in Shoulder Arthroplasty

NCT02767453

TERMINATED NA

Family Nurture Intervention in the CHoNJ NICU

NCT02352142

COMPLETED

A Retrospective Comparison of Neonatal Acid-base Status After CD Before January, 2015 and After January, 2016

NCT03455660

COMPLETED NA

Medication Adherence Telemonitoring to Reduce Heart Failure Readmissions

NCT02378571

COMPLETED NA

Fever and Wheezing Events in Children After US Influenza Vaccines Using Text Messaging

NCT02295007

COMPLETED NA

Drug User Internet and Mobile Tech Use

NCT01871298

COMPLETED NA

Interactive, Health Literacy Promoting Text Messages and HPV Vaccine Completion In Minority Adolescents

NCT02236273

COMPLETED Phase 1

Trial of AEB071 in Combination With BYL719 in Patients With Melanoma

NCT02273219

COMPLETED Phase 2

Sildenafil for Treatment of Choroidal Ischemia

NCT04356716

COMPLETED NA

Adult Influenza Vaccination Text Message Reminders With Electronic Health Record Alerts

NCT02284594

TERMINATED NA

Effect of Acid Suppression Medication on Pediatric Microbiome

NCT02016820

COMPLETED NA

Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults

NCT02347007

COMPLETED Phase 3

Topical Vancomycin for Neurosurgery Wound Prophylaxis

NCT02284126

COMPLETED NA

Impact of Sleep and Meal Timing on Food Intake Regulation

NCT02347020

COMPLETED NA

Neonatal Acid-Base Status After C Section With Maternal Tilt vs. Supine

NCT02243423

TERMINATED Phase 4

ACTHar in the Treatment of Lupus Nephritis

NCT02226341

COMPLETED Phase 2

Bone Mass and Strength After Kidney Transplantation

NCT02224144

COMPLETED Early Phase 1

N-of-1 Trials for Blood Pressure Medications in Adults

NCT02744456

COMPLETED NA

Use of Prineo in Breast Reduction Surgery

NCT01996917

COMPLETED Phase 4

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

NCT01846221

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Phase Distribution

PhaseTrial count
Phase 1 86
Phase 2 105
Phase 3 23
Phase 4 65

What is open in the Columbia University pipeline

171 recruiting of 958 indexed (18% open); 597 completed (62%).

Phase mix: 88 late (III/IV) vs 191 early (I/II) (early-phase heavy).

Top condition: Obesity (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Columbia University: open-pipeline peers nationwide

Peers matched on 958 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Columbia UniversityUniversity of MinnesotaBrigham and Women's HospitalHoffmann-La RocheUniversity of California, Los AngelesKite, A Gilead CompanyMirum PharmaceuticalsWest Virginia UniversityHospital for Special Surgery, New York
Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 958 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Columbia University page

958 registered trials is a research-attention snapshot, not an endorsement of Columbia University or any single study.

  • 171 of Columbia University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Columbia University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Columbia University pipeline card: 958 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.