Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02473276 · ClinicalTrials.gov registry record · Phase 4
2 Dose Neuraxial Morphine for Prevention of PDPH
A Phase 4 study, sponsored by Columbia University.
- Completed
- Registry status
- Phase 4
- Development phase
- 44
- Enrollment target
NCT02473276 is a Phase 4 study that has completed, run by Columbia University. The registered enrollment target is 44 participants.
The verdict
NCT02473276, a Phase 4 study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 44 participants
- Enrollment target
Study Summary
Neuraxial analgesia (most commonly continuous epidural or combined spinal epidural) is the most effective modality available for pain relief during labor. Accidental dural puncture (ADP) with a large bore epidural needle and the resulting post-dural puncture headache (PDPH) is one of the most significant sources of anesthesia-related morbidity in parturients. Epidural blood patch (EBP) is the gold standard for treatment of PDPH, and although almost always effective, can result in another ADP, as well as low back pain and lower extremity pain. For this reason, effective measures to prevent PDPH when ADP occurs would be highly valuable. One small study in which 50 women were randomly allocated to receive 2 epidural injections of morphine or saline, demonstrated a beneficial effect of epidural morphine in decreasing the incidence of PDPH. This study aims to determine the efficacy of 2 doses of neuraxial (either epidural (EPID) or intrathecal) preservative-free morphine (PFM) to prevent headache after ADP in parturients.
Interventions
- DRUG Morphine
- DRUG Sterile normal saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2015-09 |
| Est. Completion | 2020-01 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02473276
The ClinicalTrials.gov registry entry for NCT02473276 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Morphine is the first listed.
NCT02473276 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02473276 about?
NCT02473276 is a clinical study titled "2 Dose Neuraxial Morphine for Prevention of PDPH". Neuraxial analgesia (most commonly continuous epidural or combined spinal epidural) is the most effective modality available for pain relief during labor. Accidental dural puncture (ADP) with a large bore epidural needle and the resulting post-dural puncture headache (PDPH) is one of the most signif...
What is the current status of trial NCT02473276?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 44 participants. The study started on 2015-09. Estimated completion is 2020-01.
What interventions are being tested in trial NCT02473276?
The interventions under investigation include: Morphine (DRUG), Sterile normal saline (DRUG).
Who is sponsoring clinical trial NCT02473276?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.