Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02744456 · ClinicalTrials.gov registry record · Early Phase 1

N-of-1 Trials for Blood Pressure Medications in Adults

A Early Phase 1 study, sponsored by Columbia University.

Completed
Registry status
Early Phase 1
Development phase
10
Enrollment target

NCT02744456: Completed Early Phase 1 study, sponsored by Columbia University.

NCT02744456 is a Early Phase 1 study that has completed, run by Columbia University. The registered enrollment target is 10 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02744456, a Early Phase 1 study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
Early Phase 1
Development phase
10 participants
Enrollment target

Study Summary

Many patients want to know which blood pressure medication is the best for them. In this study, we will test the feasibility of a new approach to determining the best blood pressure medication for individual patients by performing an N-of-1 trial in which patients will have the opportunity to test a series of 3 blood pressure medications at escalating doses while carefully measuring their blood pressure and side-effects. At the end of each of these N-of-1 trials, we will ask patients to complete a questionnaire in which they rate their level of satisfaction with this approach to learning about which is the best blood pressure medication for them.

Primary Outcome

Question assessing helpfulness of participating in N-of-1 trial methodology with respecting to managing their hypertension

Interventions

  • DRUG Losartan
  • DRUG Amlodipine
  • DRUG Hydrochlorothiazide

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2014-08-01
Est. Completion 2017-12-31
Phase Early Phase 1
Columbia University

958 total trials

What the finished NCT02744456 record still lists

NCT02744456 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (81% lower).

The record links to 0 conditions, and to 3 interventions - of which Losartan is the first listed.

NCT02744456 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02744456 about?

NCT02744456 is a clinical study titled "N-of-1 Trials for Blood Pressure Medications in Adults". Many patients want to know which blood pressure medication is the best for them. In this study, we will test the feasibility of a new approach to determining the best blood pressure medication for individual patients by performing an N-of-1 trial in which patients will have the opportunity to test a...

What is the current status of trial NCT02744456?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2014-08-01. Estimated completion is 2017-12-31.

What interventions are being tested in trial NCT02744456?

The interventions under investigation include: Losartan (DRUG), Amlodipine (DRUG), Hydrochlorothiazide (DRUG).

Who is sponsoring clinical trial NCT02744456?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02744456's enrollment target sits among peer trials

10 1628th of 2000 higher than 256 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00623389 · 10 participants · NA

    Evaluation of an Advanced Lower Extremity Neuroprostheses

  • NCT01241864 · 10 participants · Phase 2

    Islet Transplantation in Type 1 Diabetic Kidney Allograft

  • NCT01293214 · 10 participants · NA

    Vascularized Composite Allotransplantation for Multiple Extremity Amputations

  • NCT01474148 · 10 participants · NA

    A Neuroprosthesis for Seated Posture and Balance

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02744456, the US trial registry maintained by the National Library of Medicine. NCT02744456 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.