Children's Hospital of Philadelphia

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).

431 total trials 78 currently recruiting 300 completed early-phase tilt top decile by trial count

Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Top-decile sponsor footprint

Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

431 total, page 7 of 9

COMPLETED NA

Treatment Trial of Subclinical Hypothyroidism in Down Syndrome

NCT01832753

COMPLETED NA

School Climate and Children's Behavioral Health

NCT01941069

COMPLETED NA

Peer-mentored Cooking Classes for Parents of Toddlers: Do Families Cook More and Eat Healthier After the Intervention?

NCT01710423

COMPLETED NA

Evaluation of a Shared Decision Making Portal for Pediatric Asthma

NCT01715389

COMPLETED NA

Eating RePace Study

NCT02186379

COMPLETED NA

Primary Care Transition Study

NCT01750892

COMPLETED Phase 1

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

NCT01709032

COMPLETED NA

Transitional Telehealth Home Care: REACH

NCT01941667

COMPLETED Early Phase 1

Nasal Expiratory Positive Airway Pressure for the Treatment of Pediatric Obstructive Sleep Apnea Syndrome

NCT01768065

COMPLETED NA

Comparing Driving Performance Among Trained and Untrained Drivers Using a Driving Simulator

NCT01619202

COMPLETED

Evaluation of One-day Polyethylene Glycol Powder Solution for Colonoscopy in Children

NCT01626040

COMPLETED

Hypothermia's Impact on Pharmacology

NCT01560338

COMPLETED

Optical Measurement of Cerebral Hemodynamics in Children With Acute Arterial Ischemic Stroke

NCT01786785

COMPLETED

PECARN Emergency Care Registry

NCT01657344

COMPLETED NA

Preference and Goal Directed Attention Deficit Hyperactivity Disorder Care- Pilot Study

NCT01487967

COMPLETED NA

An Evaluation of a Web-based Intervention Program for Parents and Teens to Promote Safe Driving

NCT01498575

COMPLETED Phase 2

Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases

NCT02277639

COMPLETED NA

Peers for Promoting Adolescent Transplant Health

NCT01450033

COMPLETED NA

Vitamin D3 Supplementation Pilot Study

NCT01546103

COMPLETED Phase 3

Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients

NCT01394718

COMPLETED NA

Enhancing Parenting for Depressed Caregivers

NCT01464619

COMPLETED Phase 2

Vitamin D Supplementation in HIV

NCT01475890

COMPLETED

Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery

NCT01408823

COMPLETED

Telemedicine Approaches to Evaluating Acute-phase ROP

NCT01264276

COMPLETED

MR Spectroscopy and Disease Severity Score for Gaucher in Pediatric Population

NCT01397435

COMPLETED

Genetics of Latent Autoimmune Diabetes in Adults

NCT01793974

TERMINATED Phase 2

Nasogastric/Oral Gastric Tube Placement in Infants: Comparing 2 Measurement Methods

NCT01407991

COMPLETED Phase 2

Vibrating, Cold Device for Pediatric Intravenous (IV) Cannulation Pain Relief

NCT01394250

TERMINATED

Energy Expenditure and Body Composition in Pseudohypoparathyroidism 1a

NCT01398774

COMPLETED NA

More Frequent In-Center Hemodialysis in Pediatric End Stage Renal Disease

NCT01352455

COMPLETED NA

Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease

NCT01299259

COMPLETED NA

Differences Between the Bayley-II and the Bayley-III in Very Preterm Infants at 2 Years

NCT01373177

TERMINATED NA

Proparacaine and Mydriatic Eye Drops

NCT01266824

COMPLETED

Measurement of the Quality of Pediatric CPR

NCT01265316

COMPLETED

Spine Quantitative Computed Tomography (QCT) for the Assessment of Osteoporosis on Children

NCT01330368

COMPLETED NA

Depression Prevention Initiative - A Study of Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) in School Settings

NCT01201382

COMPLETED Phase 4

Hypertonic Saline for Acute Bronchiolitis

NCT01247064

COMPLETED Phase 2

IV Glucose for Dehydration Treatment

NCT01285713

COMPLETED NA

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

NCT01808508

TERMINATED Phase 4

Bowel Preparation for Colonoscopy in Children

NCT01140295

COMPLETED NA

Comparing Use of the Glidescope Cobalt to Direct Laryngoscopy in Infants

NCT01163656

COMPLETED

Decision Making in Serious Pediatric Illness

NCT01163136

COMPLETED NA

Antimicrobial Stewardship for Primary Care Pediatricians

NCT01806103

COMPLETED Early Phase 1

Milk Oral Immunotherapy in Children to Treat Food Allergy

NCT01162473

TERMINATED NA

Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn

NCT01088997

COMPLETED NA

Giving Immunizations Through Vaccine Education

NCT01159093

COMPLETED Phase 2

Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma

NCT01162551

COMPLETED NA

Sternal Wall Pressure in the Cath Lab

NCT01117883

COMPLETED NA

Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy

NCT00986973

COMPLETED

Pharmacologic Impact on Sedation Assessments

NCT01105663

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What is open in the Children's Hospital of Philadelphia pipeline

78 recruiting of 431 indexed (18% open); 300 completed (70%).

Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).

Top condition: Pediatric Cancer (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's Hospital of Philadelphia: open-pipeline peers nationwide

Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share Children's Hospital of PhiladelphiaNovo Nordisk A/SUniversity of Illinois at ChicagoVanderbilt UniversityDartmouth-Hitchcock Medical CenterWeill Medical College of Cornell UniversityUniversity of California, BerkeleyGeorge Washington UniversityHospital for Special Surgery, New York
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 431 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Children's Hospital of Philadelphia page

431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.

  • 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.