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NCT01832753 · ClinicalTrials.gov registry record · NA
Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
A NA study of Down Syndrome and Subclinical Hypothyroidism, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 2
- Study locations
NCT01832753: Completed NA study of Down Syndrome and Subclinical Hypothyroidism, sponsored by Children's Hospital of Philadelphia.
NCT01832753 is a NA study of Down Syndrome and Subclinical Hypothyroidism that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 12 participants, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (100% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01832753, a NA study of Down Syndrome and Subclinical Hypothyroidism, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this research study is to learn about the effects of treating subclinical hypothyroidism (SCH) with thyroid hormone replacement in children and adolescents with Down syndrome (DS). We hypothesize that treatment of SCH with thyroid hormone replacement will improve cardiometabolic health and quality of life.
Primary Outcome
Lipid panel will be measured via fasting blood draw.
Conditions Studied
Interventions
- DRUG Levothyroxine
Study Locations (2)
District of Columbia
- Children's National Medical Center - Washington D.C.
Pennsylvania
- The Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2013-01 |
| Est. Completion | 2017-10-18 |
| Phase | NA |
What the finished NCT01832753 record still lists
NCT01832753 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Down Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Levothyroxine is the first listed.
NCT01832753 reports a single indexed study location in District of Columbia, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01832753 about?
NCT01832753 is a clinical study titled "Treatment Trial of Subclinical Hypothyroidism in Down Syndrome". The purpose of this research study is to learn about the effects of treating subclinical hypothyroidism (SCH) with thyroid hormone replacement in children and adolescents with Down syndrome (DS). We hypothesize that treatment of SCH with thyroid hormone replacement will improve cardiometabolic healt...
What is the current status of trial NCT01832753?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2013-01. Estimated completion is 2017-10-18.
What conditions does trial NCT01832753 study?
This clinical trial studies the following conditions: Down Syndrome, Subclinical Hypothyroidism.
What interventions are being tested in trial NCT01832753?
The interventions under investigation include: Levothyroxine (DRUG).
Who is sponsoring clinical trial NCT01832753?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01832753 being conducted?
This trial has 2 study locations across District of Columbia, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01832753's enrollment target sits among peer trials
12 51st of 54 higher than 3 of 54 other Down Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Down Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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