Children's Hospital of Philadelphia

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).

431 total trials 78 currently recruiting 300 completed early-phase tilt top decile by trial count

Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Top-decile sponsor footprint

Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

431 total, page 6 of 9

COMPLETED NA

Communication to Improve Shared Decision-Making in ADHD

NCT02716324

COMPLETED NA

Photograph Quality Rating Scale Study ("PQRS Study")

NCT03246945

COMPLETED NA

Early Literacy Promotion Intervention

NCT02713659

COMPLETED NA

A Hybrid Effectiveness-Implementation Trial of Group CBT in Urban Schools

NCT02651402

COMPLETED NA

The P4 Intervention Study to Improve Adolescent Health

NCT02554682

COMPLETED NA

Asthma Controller Adherence After Hospitalization

NCT02615743

COMPLETED NA

Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCD

NCT03632876

COMPLETED Phase 2

Milk Patch for Eosinophilic Esophagitis

NCT02579876

COMPLETED

Home or Away From Home - Descriptive Interviews (Aim 2)

NCT02794207

COMPLETED NA

Crohn Disease Exclusion Diet After Single Medication De-escalation

NCT02472457

COMPLETED NA

Impact of a Data-driven Monitor Alarm Reduction Strategy Implemented in Safety Huddles

NCT02458872

COMPLETED NA

Home Plate: A Trial to Improve Home Food Preparation Practices Among Parents of Toddlers

NCT02458833

COMPLETED Early Phase 1

Methylprednisolone Treatment of Friedreich Ataxia

NCT02424435

COMPLETED NA

Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest

NCT02458820

COMPLETED

Home Away From Home - Medical Outcomes

NCT02774850

COMPLETED

Peri-operative NIRS Monitoring In Infants

NCT02442141

COMPLETED NA

Reducing the Risk of Alarm Fatigue Through the Use of Focused Management in Safety Huddles

NCT02319421

COMPLETED NA

Cerebral Palsy Early Mobility Training

NCT02340026

COMPLETED Phase 4

Study of Pain Control With Hormonal IUS Insertion

NCT02352714

COMPLETED NA

Social Media Intervention for Postpartum Depression

NCT02355067

COMPLETED NA

Transpyloric Feeding in Severe Bronchopulmonary Dysplasia

NCT02142621

COMPLETED NA

Educating and Supporting Primary Care Providers in the Implementation of Evidence-based Practices for ADHD

NCT02271386

COMPLETED

Adolescent Idiopathic Scoliosis (AIS) Patient Positioning in EOS System®

NCT02269657

COMPLETED

Glycemic Index in Mitochondrial Disease

NCT02284334

COMPLETED Phase 3

Steroids for Pediatric Apnea Research in Kids

NCT02180672

COMPLETED NA

Video to Promote HPV Vaccination

NCT02196454

COMPLETED Phase 2

Randomized Trial of Maternal Progesterone Therapy

NCT02133573

TERMINATED

Telemedicine Approaches to Evaluating Acute-Phase ROP eROP Implementation Project

NCT02257307

COMPLETED

Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection in Children

NCT02149082

COMPLETED NA

Pediatric Continuity Care Intensivist

NCT02146573

COMPLETED NA

Ultrasound Guided IV Access in a Pediatric Emergency Department

NCT02125552

COMPLETED NA

Parent Program to Improve Child Behavior Problems

NCT02049749

COMPLETED NA

The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps

NCT02133066

COMPLETED

Energy Balance and Weight Gain With Ivacaftor Treatment

NCT02141464

COMPLETED NA

Grow2Gether Pilot Study

NCT02037490

TERMINATED Phase 3

Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair

NCT02075411

COMPLETED

Ivacaftor (Kalydeco) and Insulin in Cystic Fibrosis (CF)

NCT02039986

COMPLETED

Comparative Effectiveness of Antibiotics for Respiratory Infections

NCT02297815

COMPLETED Phase 2

BCAA Supplementation for Concussion

NCT01860404

COMPLETED NA

A Family Centered Intervention to Promote Optimal Child Development

NCT01941186

COMPLETED NA

Informing Policy to Implement Pediatric Family Engagement in Meaningful Use Stage 3

NCT01966068

COMPLETED NA

Healthy Growth Abbreviated Pilot Study

NCT01977105

COMPLETED NA

Bending Adolescent Depression Trajectories Through Personalized Prevention

NCT01948167

COMPLETED Phase 2

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

NCT01965327

COMPLETED Early Phase 1

Vouchers to Promote Tdap Vaccination

NCT01860378

COMPLETED Phase 2

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

NCT01848457

COMPLETED Early Phase 1

Asymmetrical Gait Training After Pediatric Stroke

NCT01827436

COMPLETED NA

Vitamin D Supplementation in Glomerular Disease

NCT01835639

COMPLETED NA

A Trial of "Coping Coach," a Web-based Preventive Intervention for Children

NCT01653288

COMPLETED

Down Syndrome Metabolic Health Study

NCT01821300

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What is open in the Children's Hospital of Philadelphia pipeline

78 recruiting of 431 indexed (18% open); 300 completed (70%).

Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).

Top condition: Pediatric Cancer (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's Hospital of Philadelphia: open-pipeline peers nationwide

Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share Children's Hospital of PhiladelphiaNovo Nordisk A/SUniversity of Illinois at ChicagoVanderbilt UniversityDartmouth-Hitchcock Medical CenterWeill Medical College of Cornell UniversityUniversity of California, BerkeleyGeorge Washington UniversityHospital for Special Surgery, New York
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 431 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Children's Hospital of Philadelphia page

431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.

  • 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.