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NCT02277639 · ClinicalTrials.gov registry record · Phase 2
Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases
A Phase 2 study, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- Phase 2
- Development phase
- 2
- Enrollment target
NCT02277639: Completed Phase 2 study, sponsored by Children's Hospital of Philadelphia.
NCT02277639 is a Phase 2 study that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 2 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02277639, a Phase 2 study, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 2 participants
- Enrollment target
Study Summary
This is a Phase II trial to determine the ability of a reduced intensity conditioning regimen to allow successful engraftment with CD3+ /CD19+ depleted peripheral stem cell grafts from mismatched donors. There are two conditioning regimens depending upon patient diagnosis and age.
Primary Outcome
The primary objective is to determine event free survival with durable stable engraftment of donor cells at one year.
Interventions
- DEVICE CliniMACs device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2011-11 |
| Est. Completion | 2016-03 |
| Phase | Phase 2 |
What the finished NCT02277639 record still lists
NCT02277639 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which CliniMACs device is the first listed.
NCT02277639 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02277639 about?
NCT02277639 is a clinical study titled "Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases". This is a Phase II trial to determine the ability of a reduced intensity conditioning regimen to allow successful engraftment with CD3+ /CD19+ depleted peripheral stem cell grafts from mismatched donors. There are two conditioning regimens depending upon patient diagnosis and age.
What is the current status of trial NCT02277639?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2011-11. Estimated completion is 2016-03.
What interventions are being tested in trial NCT02277639?
The interventions under investigation include: CliniMACs device (DEVICE).
Who is sponsoring clinical trial NCT02277639?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02277639's enrollment target sits among peer trials
2 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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