Children's Hospital of Philadelphia

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).

431 total trials 78 currently recruiting 300 completed early-phase tilt top decile by trial count

Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Top-decile sponsor footprint

Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

431 total, page 4 of 9

COMPLETED NA

NAD+ and Exercise in FA

NCT04192136

COMPLETED Phase 3

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

NCT04102371

TERMINATED Phase 4

Opioid-Free Anesthetic for Tonsillectomy

NCT04528173

COMPLETED Early Phase 1

RHD Genotype Matched Red Cells for Anti-D

NCT04156906

COMPLETED NA

Decision Aid for Education and Support About Cancer Treatment

NCT06191679

COMPLETED

Pediatric KIDney Stone (PKIDS) Care Improvement Network

NCT04285658

COMPLETED

Taste of Medicines in Children

NCT04220918

COMPLETED

Impact of Serious Pediatric Illness on Parent and Sibling Health

NCT03971344

COMPLETED NA

Distracted Driving App Study for Teens and Parents/Caregivers

NCT04177524

COMPLETED

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04113434

COMPLETED NA

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms

NCT04045132

COMPLETED NA

Autism and Disruptive Behavior Trial

NCT04204226

COMPLETED NA

Pilot of Enhanced Child Adult Relationship Enhancement in Pediatric Primary Care

NCT04110236

COMPLETED NA

Aligning Pulse Oximetry With Guidelines

NCT04178941

COMPLETED NA

Sleep in Pediatric HSCT

NCT04106089

COMPLETED NA

Reducing Adolescent Pregnancy

NCT04120376

COMPLETED NA

NIH R01 Friend to Friend With Coaching

NCT04164472

COMPLETED NA

Yoga-CBT Group Intervention for Adolescents With Chronic Pain and Their Caregivers

NCT04331236

COMPLETED NA

Implementing Behavioral Sleep Intervention in Urban Primary Care

NCT04046341

TERMINATED NA

A Pilot Study of Teacher-Child Interaction Training - Universal in Head Start

NCT04075071

COMPLETED NA

The Tailored Adherence Incentives for Childhood Asthma Medications (TAICAM) Trial

NCT03907410

COMPLETED NA

School Adolescent Mood Project: Efficacy of IPT-AST in Schools

NCT04109716

COMPLETED NA

Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)

NCT04124471

COMPLETED NA

Throwing Device Tracker for Youth Injury Prevention

NCT04098107

TERMINATED

Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products

NCT03886753

COMPLETED

Orkambi Treatment in 2 to 5 Year Old Children With CF

NCT03795363

COMPLETED Phase 3

Occipital Blocks for Acute Migraine

NCT03526874

COMPLETED NA

Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT

NCT03928028

COMPLETED NA

ReCoUPS: Post-Concussion Patient Reports

NCT04499937

COMPLETED NA

Increasing Childhood Sleep Duration in the Primary Care Setting

NCT03870282

COMPLETED

Ivacaftor Treatment in 4 Month to 2 Year Old CF Subjects

NCT03783286

COMPLETED NA

Evaluation of Online Training Tools in Pediatric Resuscitation

NCT03640520

COMPLETED NA

Melatonin Effects on Sleep and Circadian Rhythm in Youth and Young Adults With At-risk Symptoms

NCT03826563

COMPLETED NA

Community Health Workers and mHealth for Sickle Cell Disease Care

NCT03648710

COMPLETED NA

Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit

NCT03749330

COMPLETED NA

Prepared Parents Helping Kids

NCT03719976

COMPLETED NA

Treating IBD With Inulin

NCT03653481

COMPLETED NA

Trigger Thumb Randomized Controlled Trial

NCT03873480

TERMINATED NA

BE Smokefree: Behavioral Economics Incentives to Engage Adolescents in Smoking Cessation

NCT03670264

COMPLETED NA

The Opening Doors to Early Intervention Study

NCT03625115

COMPLETED NA

Comparison of Learning in Traditional Versus "Flipped" Classrooms

NCT03758391

COMPLETED NA

Acupuncture Intervention for AYA With Cancer

NCT03516799

COMPLETED Phase 2

Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)

NCT03551691

COMPLETED NA

MyDiaText Text Messaging Intervention for Diabetes

NCT02927639

COMPLETED NA

Aerobic Exercise for Concussion

NCT02959216

COMPLETED

Medical Cannabis Registry and Pharmacology

NCT03699527

COMPLETED Phase 2

Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

NCT03476317

TERMINATED NA

Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -

NCT03634072

COMPLETED

Multi-center Isoelectric EEG Study in Children Under General Anesthesia

NCT03432351

TERMINATED Phase 1

Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease

NCT03417999

← Previous Page 4 of 9 Next →

What is open in the Children's Hospital of Philadelphia pipeline

78 recruiting of 431 indexed (18% open); 300 completed (70%).

Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).

Top condition: Pediatric Cancer (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's Hospital of Philadelphia: open-pipeline peers nationwide

Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share Children's Hospital of PhiladelphiaNovo Nordisk A/SUniversity of Illinois at ChicagoVanderbilt UniversityDartmouth-Hitchcock Medical CenterWeill Medical College of Cornell UniversityUniversity of California, BerkeleyGeorge Washington UniversityHospital for Special Surgery, New York
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 431 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Children's Hospital of Philadelphia page

431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.

  • 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.