Children's Hospital of Philadelphia

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).

431 total trials 78 currently recruiting 300 completed early-phase tilt top decile by trial count

Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Top-decile sponsor footprint

Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

431 total, page 5 of 9

COMPLETED NA

The Videolaryngoscopy in Small Infants

NCT03396432

COMPLETED NA

BPD Saturation TARgeting

NCT03385330

COMPLETED NA

West Philadelphia Controls Asthma

NCT03514485

COMPLETED

National CounterACT Initiative

NCT03597438

COMPLETED NA

A Pilot Efficacy and Implementation Study of the Strengths Intervention Project

NCT03496155

COMPLETED NA

Integrating Community Health Workers Into the Care of Children With Type 1 Diabetes

NCT03475108

COMPLETED NA

Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes

NCT03303196

COMPLETED NA

Mobile Health Sleep and Growth Study 2

NCT03426644

COMPLETED Phase 1

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study

NCT03340805

COMPLETED NA

Tracheal Intubation Coaching in NICUs

NCT03194503

COMPLETED NA

Impact of Beds for Kids Program on Child Sleep

NCT03392844

COMPLETED

Neurology Measures in FA Children

NCT03418740

COMPLETED NA

VR Intervention to Improve Police Safety

NCT03605368

COMPLETED NA

Organizational Skills Training - Tier 2 (OST-T2)

NCT03443323

COMPLETED

Characterization of Cleft Lip and Palate Conditions in Guatemala

NCT04725370

COMPLETED NA

Delayed Cord Clamping for Congenital Diaphragmatic Hernia

NCT03314233

COMPLETED NA

Tracheostomy Change

NCT04105387

COMPLETED NA

Mobile Sleep and Growth Study

NCT03263338

COMPLETED NA

Urological and Renal Disease Engaging Adolescents in Adherence Collaborative Trial

NCT03045276

COMPLETED Phase 1

Fluid Filled Lung Oxygenation Assistance Trial

NCT03041740

COMPLETED

Clinical Evaluation of PROMIS in CKD

NCT03842293

COMPLETED NA

Distal Radius Buckle Fracture RCT

NCT04032873

COMPLETED NA

Youth mHealth Adherence Intervention for HIV+ YMSM

NCT03092115

COMPLETED NA

Food for Thought: Food Insecurity Screening in the Emergency Department

NCT03656146

COMPLETED NA

Digital Literacy Promotion

NCT03121365

COMPLETED

Neural Injury in Adolescents With Concussion

NCT03011983

COMPLETED Phase 2

Use of Pancreatic Enzymes in Short Bowel Syndrome

NCT03097029

COMPLETED NA

Microbiota-targeted Diet for Pediatric UC

NCT02922881

COMPLETED NA

Gamification and Energetic Behavior Changes

NCT03050840

COMPLETED NA

Impact of CPAP Level on V/Q Mismatch in Premature Infants

NCT02983825

COMPLETED

Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis

NCT03055455

COMPLETED NA

Parent eReferral to Tobacco Quitline

NCT02997735

COMPLETED

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

NCT02699190

COMPLETED

Microbiome, Antibiotics, and Growth Infant Cohort

NCT03001167

COMPLETED NA

Promoting Intrafamily Accountability for Reducing Cellphone Use While Driving in Adults and Their Teen Children

NCT02923271

TERMINATED NA

TubeClear® Evaluation in Pediatric Patients (Phase I)

NCT02724631

COMPLETED Phase 2

Fat Malabsorption in Chronic Pancreatitis

NCT02849704

COMPLETED NA

The ICU-Resuscitation Project (ICU-RESUS)

NCT02837497

COMPLETED

Cerebral Blood Flow and Childhood Obstructive Sleep Apnea

NCT02995837

COMPLETED

Home Away From Home - Quality of Life Surveys

NCT02777021

COMPLETED NA

Cognitive Remediation Therapy for Adolescents With Anorexia Nervosa

NCT02883413

COMPLETED NA

Aerosolized Albuterol Use in Severe BPD

NCT02766673

COMPLETED NA

Child Adult Relationship Enhancement in Pediatric Primary Care Parenting Group to Reduce Child Behavior Problems

NCT02778022

COMPLETED Phase 2

Celecoxib After Tonsillectomy

NCT02934191

COMPLETED

Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance

NCT02776098

COMPLETED Early Phase 1

Rosuvastatin (Crestor) in Friedreich Ataxia

NCT02705547

COMPLETED NA

Way to Safety Cellphone Blocking

NCT02416713

TERMINATED Phase 1

PEEP and V/Q Mismatch in Premature Infants

NCT03109613

COMPLETED

Cerebral Anatomy, Hemodynamics and Metabolism

NCT02919956

COMPLETED NA

Imaging of Lymphatic Anomalies

NCT02744027

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What is open in the Children's Hospital of Philadelphia pipeline

78 recruiting of 431 indexed (18% open); 300 completed (70%).

Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).

Top condition: Pediatric Cancer (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's Hospital of Philadelphia: open-pipeline peers nationwide

Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share Children's Hospital of PhiladelphiaNovo Nordisk A/SUniversity of Illinois at ChicagoVanderbilt UniversityDartmouth-Hitchcock Medical CenterWeill Medical College of Cornell UniversityUniversity of California, BerkeleyGeorge Washington UniversityHospital for Special Surgery, New York
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 431 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Children's Hospital of Philadelphia page

431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.

  • 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.