Case Western Reserve University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Case Western Reserve University sits in the top decile of US sponsors by registered trial count (#198 of 15,742 sponsors by registered trial count).

141 total trials 23 currently recruiting 100 completed early-phase tilt top decile by trial count

Case Western Reserve University: 141 sponsored US clinical trials, 23 recruiting.

Case Western Reserve University sponsors 141 registered US clinical trials on ClinicalTrials.gov, 23 of them currently recruiting, and 100 completed. 6 of these trials are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Bipolar Disorder, with 6 trials.

Top-decile sponsor footprint

Case Western Reserve University ranks in the top decile of sponsors by registered trial count (#198 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 83/100

100 of 103 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (97.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

141 total, page 2 of 3

COMPLETED

Self-Management and Resilience Trajectories in African American Adults With Hypertension

NCT05308914

COMPLETED NA

An Intervention to Promote Use of Smoking Cessation Resources Among Adults Using Community Food Pantries

NCT05273450

COMPLETED NA

An Intervention to Promote Smoking Cessation Among Adults With Food Insecurity

NCT05259852

COMPLETED NA

Impact of Donor Diabetes on DMEK Success and Endothelial Cell Loss

NCT05134480

COMPLETED

IMAS Optimization and Applicability in Acute and Subacute Stroke.

NCT05469438

COMPLETED NA

Positive Processes and Transition to Health

NCT04678232

COMPLETED NA

Acupuncture in the Emergency Department for Pain Management

NCT04880733

COMPLETED NA

Improving Adherence in Adolescents and Young Adults With Bipolar Disorder

NCT04348604

COMPLETED NA

Offering Support and Electronic Resources for Care Partners of Those With Multiple Sclerosis

NCT04662008

COMPLETED NA

Assess and Adapt to the Impact of COVID-19 on CVD Self-Management and Prevention Care in Adults Living With HIV

NCT04661813

COMPLETED NA

Self-Management Intervention: Considering Needs & Preferences of Dementia Caregivers (Caregiver Career Study)

NCT04603482

COMPLETED NA

Pictographic Education Handout on Tracheostomy Care

NCT05176236

COMPLETED NA

Reducing Stroke Risk in African-American Men

NCT04402125

COMPLETED NA

A Dietary Intervention Study on the Microbiome in Crohn's Disease Patients

NCT04065048

COMPLETED NA

A Nurse-led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention

NCT03643705

COMPLETED NA

Older Adult Effectiveness of 2 Treatments

NCT03916926

COMPLETED Early Phase 1

Diabetes Inspired Culinary Education

NCT05160142

COMPLETED NA

Tailored Health Self-Management Interventions for Highly Distressed Caregivers: Family Members of Persons With Dementia

NCT04247347

TERMINATED Phase 2

HIV Reservoir Reduction With Interleukin-2

NCT03308786

COMPLETED NA

Fatigue Management Programs for People With MS

NCT03550170

COMPLETED NA

A COmmunity and Tech-Based ApproaCh for Hypertension Self-MANagement

NCT03724487

COMPLETED NA

TRANSLATE: Transgender and Gender Nonconforming Individuals' Access to Healthcare

NCT03808883

COMPLETED Phase 1

Project 2 Airway Potential Hydrogen (pH) in Asthma

NCT03617718

COMPLETED NA

Technology-based Intervention and Positive Psychological Training for Blood Pressure Control in African Americans

NCT03722667

COMPLETED NA

Testing TRUST Depression Management Intervention

NCT03599141

COMPLETED

Measuring Brain Activity of School Age Children

NCT03407729

COMPLETED Phase 1

Efavirenz for Patients With Alzheimer's Disease

NCT03706885

COMPLETED NA

Providers Against Cavities in Children's Teeth

NCT03385629

COMPLETED NA

Partnering Physical and Emotional Fitness: Improving Cardiac Recovery With Training in Emotion Regulation

NCT03303703

COMPLETED Phase 4

Neuroimaging During Pure Oxygen Breathing

NCT03268590

COMPLETED NA

The Grandmother Study: Grandmother Initiatives in Family Transformation

NCT03263923

COMPLETED NA

Tailored Health Self-Management Interventions for Highly Distressed Family Caregivers

NCT03023332

COMPLETED NA

Medication Adherence in Hypertensive Individuals With Bipolar Disorder

NCT02983877

COMPLETED NA

Self-Management Behaviors of Caregivers of the Chronically Critically Ill

NCT03065829

COMPLETED NA

Building Resilience After Childhood Emergencies (BRACE)

NCT02898883

TERMINATED NA

Organ Donation Interventions Among High Students

NCT02585921

COMPLETED NA

Decision Support Among Surrogate Decision Makers of the Chronically Critically Ill (INVOLVE)

NCT03099746

COMPLETED NA

Family Access to Dentist Study

NCT02395120

COMPLETED NA

Direct Comparison of Spinal Cord Stimulator Parameter Settings

NCT05283863

COMPLETED NA

Handheld Mirror to Improve Child's Behavior During Dental Treatment

NCT02366520

TERMINATED NA

Helium-oxygen Gas Mixtures Delivered by a High Flow Nasal Cannula in Bronchiolitis

NCT02373683

COMPLETED NA

A Clinical Trial of SystemCHANGE to Improve Exercise, Diet and Health in HIV-Infected Adults

NCT02553291

COMPLETED NA

Self-management for People With Epilepsy and a History of Negative Health Events

NCT02970396

COMPLETED Phase 1

AIDS 347: IL-6 Blockade in Treated HIV Infection

NCT02049437

COMPLETED NA

Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis

NCT02202577

COMPLETED NA

e-Mobile Tablet for People With Chronic Conditions

NCT02833311

COMPLETED NA

University Student Intervention to Increase Organ Donation

NCT01969864

COMPLETED NA

Targeted Self-Management for Epilepsy and Serious Mental Illness (TIME)

NCT01992393

COMPLETED NA

Home or Office Visit for the Insertion of Implantable Birth Control

NCT01816932

COMPLETED Phase 2

Randomized Trial of an HIV Navigation Program for Early Palliative Care

NCT01884389

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 4
Phase 3 2
Phase 4 4

What is open in the Case Western Reserve University pipeline

23 recruiting of 141 indexed (16% open); 100 completed (71%).

Phase mix: 6 late (III/IV) vs 10 early (I/II) (early-phase heavy).

Top condition: Bipolar Disorder (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Case Western Reserve University: open-pipeline peers nationwide

Peers matched on 141 registered trials and 16% open enrollment, not the therapeutic-area sidebar.

Case Western Reserve University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20% Total trials Recruiting share Case Western Reserve UniversityEastern Cooperative Oncology GroupPurdue UniversityJohnson & Johnson Vision CareMclean HospitalDrexel UniversityH. Lee Moffitt Cancer Center and Research InstituteAtlantic Health SystemBioMarin Pharmaceutical
Case Western Reserve University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Case Western Reserve University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 141 trials (± recruiting share)

Sponsors near 16% open enrollment (± trial volume)

What to do with this Case Western Reserve University page

141 registered trials is a research-attention snapshot, not an endorsement of Case Western Reserve University or any single study.

  • 23 of Case Western Reserve University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Bipolar Disorder is the condition Case Western Reserve University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Bipolar Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Case Western Reserve University pipeline card: 141 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.