Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Periodontal Diseases: early-phase trial registry
8 of 16 indexed Periodontal Diseases trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,060 of 28,707 conditions by registered trial count.
16 US clinical trials · 8 currently recruiting · #1,060 of 28,707 conditions by registered trial count
Periodontal Diseases: 16 US clinical trials tracked, 8 recruiting.
Periodontal Diseases is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is The Forsyth Institute, running 2 of these trials.
Enrollment posture brief
Registry condition periodontal-diseases
OPEN 8 | RECR 50% | LATE 1 | EARLY 2 | RANK #1060 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Periodontal Diseases lists 8 open slots (50% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Periodontal Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Periodontal Diseases is recruiting above its size-band peers.
8 of 16 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Periodontal Diseases trials is spread across many organizations.
The Forsyth Institute accounts for 2 of 16 trials (12.5%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Periodontal Diseases enrolment sits around 76 participants.
Median target enrolment is 76 among the 16 trials that report a genuine target (sentinel values excluded). 9 of those (56.3%) plan for fewer than 100 participants.
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Periodontal Diseases research is mostly interventional.
14 interventional and 2 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
16 total, page 1 of 1
Oral Health Intervention in Adult Primary Care
Case Western Reserve University
NCT06555029
Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
Rutgers, The State University of New Jersey
NCT06131021
Oral Health In Cirrhosis of the Liver (ORACLE)
Hunter Holmes Mcguire Veteran Affairs Medical Center
NCT06052150
F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)
Georgetown University
NCT06315855
Novel Dental Gel as an Adjunct to Scaling and Root Planing
University of Alabama at Birmingham
NCT05384132
An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis
Erchonia Corporation
NCT06656325
Microsurgery and Periodontal Healing
The University of Texas Health Science Center at San Antonio
NCT07054008
Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement
Case Western Reserve University
NCT06149585
Addition of Dehydrated Human Amnion-Chorion Membrane During Scaling and Root Planing
University of Colorado, Denver
NCT03836378
Study Comparing Two Different Methods of Treating Periodontal Disease
The Forsyth Institute
NCT00127244
Microbial Associations in Periodontal Health and Disease
The Forsyth Institute
NCT00066001
Impact of Brief Motivational Interviewing on Periodontal Clinical Outcomes: a 3-year Post-trial Follow-up
University of Minnesota
NCT05336396
Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis
Glo Science
NCT02906982
Treatment of Periodontitis With Er:YAG Laser
Columbia University
NCT03628872
Application of L-PRF in Periodontal Surgery
The University of Texas Health Science Center at San Antonio
NCT06296498
Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease
The University of Texas Health Science Center, Houston
NCT05252000
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Periodontal Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Periodontal Diseases trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Periodontal Diseases page
16 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Periodontal Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- The Forsyth Institute sponsors the most Periodontal Diseases trials on record, review their full trial history before evaluating a specific study. See The Forsyth Institute's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Periodontal Diseases condition card totals 16 registered trials; most-linked intervention Gum health formulation on toothbrush; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.