Case Comprehensive Cancer Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Case Comprehensive Cancer Center sits in the top decile of US sponsors by registered trial count (#90 of 15,742 sponsors by registered trial count).

407 total trials 55 currently recruiting 257 completed early-phase tilt top decile by trial count

Case Comprehensive Cancer Center: 407 sponsored US clinical trials, 55 recruiting.

Case Comprehensive Cancer Center sponsors 407 registered US clinical trials on ClinicalTrials.gov, 55 of them currently recruiting, and 257 completed. 13 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 18 trials.

Top-decile sponsor footprint

Case Comprehensive Cancer Center ranks in the top decile of sponsors by registered trial count (#90 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 37/100

257 of 325 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (79.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

407 total, page 7 of 9

COMPLETED Phase 1

CC-4047 in Treating Patients With Advanced Solid Tumors That Did Not Respond to Treatment

NCT00482521

COMPLETED Phase 2

Sunitinib in Treating Patients With Kidney Cancer That Cannot Be Removed by Surgery

NCT00459979

COMPLETED NA

Radiosurgery in Treating Patients With Kidney Tumors

NCT00458484

TERMINATED

Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer

NCT00899132

COMPLETED

Changes in Breast Density and Breast Cancer Risk in Women With Breast Cancer and in Healthy Women

NCT00445445

TERMINATED Phase 2

Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery

NCT01340599

COMPLETED Phase 2

Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

NCT00460031

COMPLETED Phase 2

GM-CSF in Treating Patients With Relapsed Prostate Cancer

NCT00908141

COMPLETED NA

Stress Reduction Program in Patients With Malignant Brain Tumors and Their Family Caregivers

NCT00376818

COMPLETED Phase 2

Celecoxib and Recombinant Interferon Alfa-2b in Metastatic Kidney Cancer Who Have Undergone Surgery

NCT01158534

TERMINATED Phase 1

Dose Dense Therapy and Bevacizumab in Solid Tumors and Colorectal Cancer

NCT00296062

COMPLETED Phase 2

Sorafenib in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Sunitinib or Bevacizumab

NCT00866320

COMPLETED

Caregiver Support in the Quality of Life of Patients Who Are Undergoing Donor Bone Marrow Transplantation

NCT00281801

COMPLETED

Changes in Muscle Tissue in Patients With Pancreatic Cancer

NCT00369460

COMPLETED Phase 3

Study of Tamsulosin and/or Dutasteride to Relieve Urinary Symptoms After Brachytherapy for Localized Prostate Cancer

NCT00244309

COMPLETED

Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid Tumors

NCT00305799

TERMINATED Phase 2

RAD001(Everolimus) in Treating Patients With Myelodysplastic Syndromes

NCT00809185

COMPLETED Phase 2

Radiotherapy,Chemotherapy,Before and After Surgery in Advanced Esophageal or Gastroesophageal Junction Cancer

NCT00258323

COMPLETED Phase 2

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative Disorder

NCT00274820

COMPLETED Phase 2

Gemcitabine and Docetaxel in Treating Patients With Metastatic Prostate Cancer

NCT00276549

COMPLETED Phase 2

Gefitinib in Treating Patients With Recurrent or Metastatic Esophageal or Gastroesophageal Junction Cancer

NCT00268346

COMPLETED Phase 2

Bevacizumab, Docetaxel, and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer

NCT00281840

COMPLETED Early Phase 1

Cryotherapy for Barrett's Esophagus and Early Esophageal Cancers

NCT00650988

COMPLETED

Quality of Life of Older Patients Who Are Undergoing Treatment for Cancer and of Their Family Caregivers

NCT00255697

COMPLETED Phase 1

Lenalidomide and Docetaxel in Treating Patients With Advanced Solid Tumors

NCT00253344

COMPLETED

Biological Markers in Patients With Pancreatic Cancer Experiencing Weight Loss

NCT00899158

COMPLETED

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

NCT00255671

COMPLETED NA

Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy.

NCT00258401

COMPLETED

Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer

NCT00281853

COMPLETED Phase 3

High Light and Low Light Dose PDT in Glioma

NCT00118222

COMPLETED Phase 1

Erlotinib, Modified FOLFOX6, and Bevacizumab as First-Line Therapy Metastatic Colorectal Cancer

NCT00118261

COMPLETED NA

Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid Tumors

NCT00263861

COMPLETED Phase 2

Interferon Alfa (IFN-Alpha-1b) in Renal Cancer With Metastatic Kidney Cancer

NCT00278174

COMPLETED NA

Lifestyle Change and Quality of Life in Obese Patients With Stage I/II Endometrial Cancer in Remission

NCT00262938

COMPLETED Phase 2

Campath-1H + FK506 and Methylprednisolone for GVHD

NCT00109993

COMPLETED

Study of Calgranulin A/B Levels in Patients With Newly Diagnosed Stage I,II,III Breast Cancer

NCT00900133

TERMINATED Early Phase 1

11C Topotecan PET Imaging

NCT00253461

COMPLETED Phase 1

Donor Mesenchymal Stem Cell Infusion in Treating Patients With Acute or Chronic Graft-Versus-Host Disease After Undergoing a Donor Stem Cell Transplant

NCT00361049

COMPLETED Phase 1

Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides

NCT00103246

COMPLETED Phase 3

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Liposomal Doxorubicin for Cancer

NCT00245050

COMPLETED Phase 2

Interferon Beta in Treating Patients With Metastatic Cutaneous Melanoma or Ocular Melanoma

NCT00085306

TERMINATED Phase 2

Topotecan in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

NCT00087048

TERMINATED Phase 1

Induction Chemotherapy Using Doxorubicin and Cisplatin Followed by Combretastatin A4 Phosphate and Radiation Therapy in Treating Patients With Newly Diagnosed Regionally Advanced Anaplastic Thyroid Cancer

NCT00077103

TERMINATED Phase 1

Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer

NCT00075673

COMPLETED Phase 3

Gemcitabine and Carboplatin Followed By Docetaxel in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT00074204

COMPLETED Phase 2

Two Regimens of Docetaxel in Treating Patients Who Have Not Received Chemotherapy For Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT00075374

COMPLETED Phase 1

HER-2 Protein Vaccine in Treating Women With Breast Cancer

NCT00068614

COMPLETED NA

Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies

NCT00068523

COMPLETED Phase 2

Combretastatin A4 Phosphate in Treating Patients With Advanced Anaplastic Thyroid Cancer

NCT00060242

COMPLETED Phase 1

GW786034 in Treating Patients With Advanced Solid Tumors

NCT00060151

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 116
Phase 3 12
Phase 4 1

What is open in the Case Comprehensive Cancer Center pipeline

55 recruiting of 407 indexed (14% open); 257 completed (63%).

Phase mix: 13 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (18 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Case Comprehensive Cancer Center: open-pipeline peers nationwide

Peers matched on 407 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 10%15%20%25% Total trials Recruiting share Case Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterSt. Jude Children's Research HospitalBeth Israel Deaconess Medical CenterWayne State UniversityUniversity of MichiganAlbany Medical College
Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 407 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Case Comprehensive Cancer Center page

407 registered trials is a research-attention snapshot, not an endorsement of Case Comprehensive Cancer Center or any single study.

  • 55 of Case Comprehensive Cancer Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Case Comprehensive Cancer Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Case Comprehensive Cancer Center pipeline card: 407 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.