Case Comprehensive Cancer Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Case Comprehensive Cancer Center sits in the top decile of US sponsors by registered trial count (#90 of 15,742 sponsors by registered trial count).

407 total trials 55 currently recruiting 257 completed early-phase tilt top decile by trial count

Case Comprehensive Cancer Center: 407 sponsored US clinical trials, 55 recruiting.

Case Comprehensive Cancer Center sponsors 407 registered US clinical trials on ClinicalTrials.gov, 55 of them currently recruiting, and 257 completed. 13 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 18 trials.

Top-decile sponsor footprint

Case Comprehensive Cancer Center ranks in the top decile of sponsors by registered trial count (#90 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 37/100

257 of 325 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (79.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

407 total, page 3 of 9

TERMINATED NA

Liquid Biopsy to Reduce Time to Treatment for Advanced Nonsquamous NSCLC Diagnosed at Outside Sites

NCT04474613

COMPLETED Phase 1

Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer

NCT04357587

COMPLETED Phase 1

Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N

NCT04323202

COMPLETED Phase 2

Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes

NCT04187833

COMPLETED NA

C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)

NCT04358705

TERMINATED Phase 2

Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma

NCT04322643

COMPLETED NA

Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies

NCT04332419

COMPLETED NA

Effects of Early Palliative Care Integration on Patients With Newly Diagnosed Multiple Myeloma

NCT04248244

TERMINATED Phase 3

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

NCT04176419

COMPLETED Phase 2

Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses

NCT04140292

COMPLETED NA

Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients

NCT04055948

COMPLETED NA

DRIHNC - Dehydration Reduction in Head & Neck Cancer

NCT03799380

COMPLETED

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

NCT05079113

COMPLETED NA

Incomplete Follow Up After Positive FIT or Stool DNA Testing: A Multimethod Approach

NCT03817905

TERMINATED Early Phase 1

Proton Based Cardiac Sparing Accelerated Fractionated RadioTherapy in Unresectable NSCLC

NCT03818776

COMPLETED Phase 2

Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma

NCT04051606

TERMINATED Phase 2

CPX-351 Therapy for MDS After Hypomethylating Agent Failure

NCT03957876

TERMINATED NA

Improving Sexual Health in Gynecologic Cancer Patients

NCT03827993

COMPLETED Early Phase 1

18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis

NCT03930173

COMPLETED

Enhancing SUV Accuracy of PET/MR for Clinical Trial Qualification

NCT03603925

COMPLETED NA

Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers

NCT03927976

COMPLETED

Assessing the Impact of the Microbiome on Breast Cancer Radiotherapy Toxicity

NCT04245150

COMPLETED NA

Prehabilitation in Pancreatic Surgery

NCT03688867

COMPLETED NA

Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans

NCT03640208

COMPLETED NA

Role of Magnetic Resonance Fingerprinting and Quantitative MR Imaging in Breast Cancer

NCT03650803

COMPLETED NA

Innovations to Prevent Relapse Among Low-income African American Smokers

NCT03982576

COMPLETED NA

Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma

NCT03768856

COMPLETED Phase 1

Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC

NCT03535363

COMPLETED Phase 1

Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma

NCT03467789

COMPLETED NA

Improved Intra-operative Safety From Optimal Selection of Anti-slip Surface

NCT03573557

COMPLETED

Intra-procedural 360-degree Display for Performing Percutaneous Liver Tumor Ablation

NCT03500757

COMPLETED NA

Path2Quit Tobacco Intervention For African Americans

NCT03524482

COMPLETED Phase 2

Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation

NCT03342196

COMPLETED Phase 2

TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid

NCT03397173

COMPLETED

A Pilot Study of [Ga-68]PSMA PET/MRI for the Assessment of PSMA-positive Tumors

NCT02978586

COMPLETED NA

Endoesophageal Brachytherapy for Patients With Esophageal Cancer

NCT03335813

COMPLETED NA

3D Printed Models in Mohs Micrographic Surgery

NCT03461965

COMPLETED NA

Music Therapy and Hematopoietic Stem Cell Transplant

NCT03378089

COMPLETED NA

Using Decision Analysis to Enhance Decision-Making Regarding Prostate Cancer Screening

NCT03387527

COMPLETED NA

Debulking Surgery in Ovarian Cancer

NCT03378128

COMPLETED Early Phase 1

End Nicotine Dependence Clinic

NCT03290430

COMPLETED NA

Getting Ahead for Cancer Control

NCT03247634

COMPLETED NA

Feasibility of a Social Media-based Weight Loss Program for Low Socioeconomic Status Individuals

NCT03337230

COMPLETED NA

Utilizing the Arts to Improve Health, Resilience, and Well-Being Among Cancer Patients and Their Caregivers

NCT03272880

COMPLETED NA

Correlative Analysis of the Genomics of Vitamin D and Omega-3 Fatty Acid Intake in Prostate Cancer

NCT03290417

COMPLETED Early Phase 1

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

NCT02970448

COMPLETED Phase 2

Intermittent Therapy in Metastatic Renal Cell Carcinoma Patients Treated With Ipilimumab and Nivolumab

NCT03126331

TERMINATED NA

Evaluating the Impact of Video Discharge Instructions for Mohs Surgery Post-Operative Care

NCT02970435

COMPLETED NA

Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer

NCT03190083

COMPLETED Phase 2

Pembrolizumab Alone or Sequentially Following Single Fraction Non-ablative Radiation to One of the Target Lesions, in Previously Treated Patients With Stage IV NSCLC

NCT02658097

← Previous Page 3 of 9 Next →

Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 116
Phase 3 12
Phase 4 1

What is open in the Case Comprehensive Cancer Center pipeline

55 recruiting of 407 indexed (14% open); 257 completed (63%).

Phase mix: 13 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (18 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Case Comprehensive Cancer Center: open-pipeline peers nationwide

Peers matched on 407 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 10%15%20%25% Total trials Recruiting share Case Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterSt. Jude Children's Research HospitalBeth Israel Deaconess Medical CenterWayne State UniversityUniversity of MichiganAlbany Medical College
Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Case Comprehensive Cancer Center sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 407 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Case Comprehensive Cancer Center page

407 registered trials is a research-attention snapshot, not an endorsement of Case Comprehensive Cancer Center or any single study.

  • 55 of Case Comprehensive Cancer Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Case Comprehensive Cancer Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Case Comprehensive Cancer Center pipeline card: 407 registered trials from official public datasets.Report a data error.