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NCT04176419 · ClinicalTrials.gov registry record · Phase 3
Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery
A Phase 3 study, sponsored by Case Comprehensive Cancer Center.
- Terminated
- Registry status
- Phase 3
- Development phase
- 30
- Enrollment target
NCT04176419: Clinical Trial Phase 3 study, sponsored by Case Comprehensive Cancer Center.
NCT04176419 is a Phase 3 study that was terminated before completion, run by Case Comprehensive Cancer Center. The registered enrollment target is 30 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04176419, a Phase 3 study, was terminated before completion, sponsored by Case Comprehensive Cancer Center.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 30 participants
- Enrollment target
Study Summary
The purpose of this study is to determine how a non-opioid pain control regimen, administered before and during surgery, will affect postoperative pain control and total opioid consumption in head and neck cancer participants undergoing cancer surgery with free flap reconstruction.
Primary Outcome
Total opioid consumption measured in daily morphine equivalent
Interventions
- DRUG Acetaminophen
- DRUG Ketamine
- DRUG Lidocaine
- DRUG Placebo Ketamine
- DRUG Placebo Lidocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-01-17 |
| Est. Completion | 2021-06-23 |
| Phase | Phase 3 |
Why NCT04176419 stopped before completion
NCT04176419 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 5 interventions - of which Acetaminophen is the first listed.
NCT04176419 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04176419 about?
NCT04176419 is a clinical study titled "Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery". The purpose of this study is to determine how a non-opioid pain control regimen, administered before and during surgery, will affect postoperative pain control and total opioid consumption in head and neck cancer participants undergoing cancer surgery with free flap reconstruction.
What is the current status of trial NCT04176419?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2020-01-17. Estimated completion is 2021-06-23.
What interventions are being tested in trial NCT04176419?
The interventions under investigation include: Acetaminophen (DRUG), Ketamine (DRUG), Lidocaine (DRUG), Placebo Ketamine (DRUG), Placebo Lidocaine (DRUG).
Who is sponsoring clinical trial NCT04176419?
This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04176419's enrollment target sits among peer trials
30 1917th of 2000 higher than 68 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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