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NCT01290237 · ClinicalTrials.gov registry record · NA

Use of a Loading Dose of Vancomycin in Pediatric Dosing

A NA study, sponsored by Boston Children's Hospital.

Terminated
Registry status
NA
Development phase
59
Enrollment target

NCT01290237: Clinical Trial NA study, sponsored by Boston Children's Hospital.

NCT01290237 is a NA study that was terminated before completion, run by Boston Children's Hospital. The registered enrollment target is 59 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01290237, a NA study, was terminated before completion, sponsored by Boston Children's Hospital.

TERMINATED
Registry status
NA
Development phase
59 participants
Enrollment target

Study Summary

Vancomycin is an antibiotic administered to children or adults for many types of infections. While it has been used to treat infections of children for more than 50 years we are still not completely certain about the best dose to use when starting treatment with this medication. This study is intended to evaluate whether giving a new higher dose of vancomycin for the first dose will help us get to the desired amount in the body more quickly then the usual first dose. Half of the patients would get the new higher dose and the other half of patients will get the typical first dose. Only the first dose is changed and all doses that follow are the same in both groups and are doses typically used for children.

Primary Outcome

proportion of participants whose vancomycin trough was between 15 and 20 mcg/mL, 8 hours after the first vancomycin dose, in loading dose group as compared to control group

Interventions

  • DRUG vancomycin hydrocloride

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2011-02
Est. Completion 2012-03
Phase NA
Boston Children's Hospital

462 total trials

Why NCT01290237 stopped before completion

NCT01290237 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which vancomycin hydrocloride is the first listed.

NCT01290237 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01290237 about?

NCT01290237 is a clinical study titled "Use of a Loading Dose of Vancomycin in Pediatric Dosing". Vancomycin is an antibiotic administered to children or adults for many types of infections. While it has been used to treat infections of children for more than 50 years we are still not completely certain about the best dose to use when starting treatment with this medication. This study is inten...

What is the current status of trial NCT01290237?

This trial is currently terminated. It is a NA study. The enrollment target is 59 participants. The study started on 2011-02. Estimated completion is 2012-03.

What interventions are being tested in trial NCT01290237?

The interventions under investigation include: vancomycin hydrocloride (DRUG).

Who is sponsoring clinical trial NCT01290237?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01290237's enrollment target sits among peer trials

59 1256th of 2000 higher than 745 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01290237, the US trial registry maintained by the National Library of Medicine. NCT01290237 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.