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NCT02772783 · ClinicalTrials.gov registry record · NA
Dietary Glycemic Index, Brain Function and Food Intake in Patients With Type 1 Diabetes Mellitus
A NA study, sponsored by Boston Children's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT02772783 is a NA study that has completed, run by Boston Children's Hospital. The registered enrollment target is 15 participants.
The verdict
NCT02772783, a NA study, has completed, sponsored by Boston Children's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Processed carbohydrates cause rapid changes in blood sugar and have been associated with overeating and obesity. We have shown that test meals high in processed carbohydrate affect brain areas involved in addiction, craving and overeating. It is unknown whether the changes in blood sugar or the associated higher insulin levels mediate this brain activation and its likely adverse effects. Answering this question is important for patients with type 1 diabetes who have elevated risks of obesity and disordered eating: If blood sugar is the causal mechanism, optimal insulin coverage should be protective. If insulin is the causal mechanism, however, a diet high in processed carbohydrate could predispose to overeating and weight gain, as this diet requires higher insulin doses. To disentangle these factors, we will study brain activation and relevant blood markers in 15 men with diabetes. In 4 sessions, we will examine meals with differential carbohydrate properties while giving insulin infusions.
Interventions
- OTHER high GI meal
- OTHER low GI meal
- DRUG euglycemic insulin clamp
- DRUG primed-variable insulin infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2016-07 |
| Est. Completion | 2018-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02772783
The ClinicalTrials.gov registry entry for NCT02772783 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which high GI meal is the first listed.
NCT02772783 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02772783 about?
NCT02772783 is a clinical study titled "Dietary Glycemic Index, Brain Function and Food Intake in Patients With Type 1 Diabetes Mellitus". Processed carbohydrates cause rapid changes in blood sugar and have been associated with overeating and obesity. We have shown that test meals high in processed carbohydrate affect brain areas involved in addiction, craving and overeating. It is unknown whether the changes in blood sugar or the asso...
What is the current status of trial NCT02772783?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2016-07. Estimated completion is 2018-05.
What interventions are being tested in trial NCT02772783?
The interventions under investigation include: high GI meal (OTHER), low GI meal (OTHER), euglycemic insulin clamp (DRUG), primed-variable insulin infusion (DRUG).
Who is sponsoring clinical trial NCT02772783?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
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