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NCT02140268 · ClinicalTrials.gov registry record · Phase 1
To Evaluate the Effect of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy Volunteers
A Phase 1 study of Healthy Volunteers, sponsored by Ardelyx.
- Completed
- Registry status
- Phase 1
- Development phase
- 65
- Enrollment target
- 1
- Study location
NCT02140268: Completed Phase 1 study of Healthy Volunteers, sponsored by Ardelyx.
NCT02140268 is a Phase 1 study of Healthy Volunteers that has completed, run by Ardelyx. The registered enrollment target is 65 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02140268, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Ardelyx.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 65 participants
- Enrollment target
- 1
- Study location
Study Summary
A Study to Evaluate the Effects of oral repeated doses of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy Volunteers
Primary Outcome
Change in plasma area under the concentration-time curve (AUC) and maximal plasma concentration (Cmax) of midazolam after AZD1722 administration
Conditions Studied
Interventions
- DRUG Midazolam
- DRUG AZD1722
- DRUG AZD1722 and Midazolam
Study Locations (1)
Kansas
- Research Site - Overland Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2014-05 |
| Est. Completion | 2014-08 |
| Phase | Phase 1 |
What the finished NCT02140268 record still lists
NCT02140268 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 3 interventions - of which Midazolam is the first listed.
NCT02140268 reports a single indexed study location in Kansas.
Frequently Asked Questions
What is clinical trial NCT02140268 about?
NCT02140268 is a clinical study titled "To Evaluate the Effect of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy Volunteers". A Study to Evaluate the Effects of oral repeated doses of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy Volunteers
What is the current status of trial NCT02140268?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 65 participants. The study started on 2014-05. Estimated completion is 2014-08.
What conditions does trial NCT02140268 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT02140268?
The interventions under investigation include: Midazolam (DRUG), AZD1722 (DRUG), AZD1722 and Midazolam (DRUG).
Who is sponsoring clinical trial NCT02140268?
This trial is sponsored by Ardelyx, which has 25 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02140268 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteers
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02140268's enrollment target sits among peer trials
65 104th of 283 higher than 179 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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